Department of Life Sciences and Systems Biology, University of Torino, Torino, Italy.
Edoardo Agnelli Hospital, Gynaecology and Obstetrics Division, Pinerolo, Italy.
Eur J Clin Nutr. 2022 Apr;76(4):604-609. doi: 10.1038/s41430-021-00990-7. Epub 2021 Aug 6.
BACKGROUND/OBJECTIVES: During pregnancy, body composition alterations can be considered as markers of complications and in this context, a non-invasive and low-cost method such as Bioelectrical Impedance Vector Analysis (BIVA), can be employed to monitor such changes. This study aimed at identifying body compartments trend during physiological pregnancy.
SUBJECTS/METHODS: Classic and specific BIVA variables have been measured in a sample of 37 pregnant women approximately every 4 weeks of gestation and once postpartum. Researchers used both longitudinal and cross-sectional approach. The first case included data of women from the 11th to the 15th week along with data from the 28th to the 32nd week of gestation. The cross-sectional approach regarded two more specific moments (11th-12th weeks and 30th-31st weeks) and data within two months postpartum RESULTS: The longitudinal approach showed a significant decrease in classic BIVA variables (R/H, Xc/H, Z/H p < 0.001) and a shortening of the vector, pointing out that TBW and hydration increased significantly. Specific vector length increased significantly, indicating a physiological gain of FM% (p < 0.01). The cross-sectional approach showed lower values of R/H, Xc/H, Z/H between 12th-13th and 30th-31st weeks (p < 0.01), while in the postpartum period values tended to those registered at the beginning of pregnancy. No changes have been found for the phase angle in both approaches, indicating that ECW/ICW ratio remained constant CONCLUSIONS: Among physiological pregnancies, bioelectric values showed a coherent trend and these results represent a first contribution to support routine exams, leading to an early detection of anomalous values potentially correlated to pathologies.
背景/目的:在怀孕期间,身体成分的改变可以被视为并发症的标志物,在这种情况下,可以使用生物电阻抗向量分析(BIVA)等非侵入性和低成本的方法来监测这些变化。本研究旨在确定生理妊娠期间身体成分的变化趋势。
受试者/方法:对 37 名孕妇的样本进行了经典和特定的 BIVA 变量测量,大约每 4 周进行一次妊娠,一次产后测量。研究人员采用了纵向和横断面两种方法。第一个案例包括第 11 周到第 15 周以及第 28 周到第 32 周的妊娠数据。横断面方法还考虑了两个更具体的时间点(第 11-12 周和第 30-31 周)以及产后两个月内的数据。
纵向方法显示经典 BIVA 变量(R/H、Xc/H、Z/H,p<0.001)显著下降,向量缩短,表明 TBW 和水合作用显著增加。特定向量长度显著增加,表明 FM% 生理性增加(p<0.01)。横断面方法显示第 12-13 周和第 30-31 周之间 R/H、Xc/H、Z/H 值较低(p<0.01),而在产后阶段,这些值趋于妊娠早期的水平。两种方法的相位角均未发生变化,表明 ECW/ICW 比值保持不变。
在生理妊娠中,生物电阻值显示出一致的趋势,这些结果代表了对支持常规检查的初步贡献,从而可以早期发现与疾病相关的异常值。