Wang Yangyang, Wu Hongmei, Zhen Wenqiang, Gong Tao, Li Duan, Cai Yao, Fan Shiyi
College of Chemistry and Chemical Engineering, University of South China, Hengyang, 421000.
Zhongguo Yi Liao Qi Xie Za Zhi. 2021 Jul 30;45(4):410-415. doi: 10.3969/j.issn.1671-7104.2021.04.013.
Biodegradable vascular stents have better biocompatibility than drug-eluting stents. The blood vessels are rebuilt and degraded after normal physiological functions are restored. Due to it will not stay in the body for a long time and the patients don't need taking anti-rejection drugs all the time, it becomes the focus of attention in the treatment of coronary heart disease. This article introduced the development history of biodegradable stents and reviewed the research status of several different materials of vascular stents (animals or humans) and pointed out the existing problems. And it also predicted the research direction of biodegradable vascular stents.
可生物降解血管支架比药物洗脱支架具有更好的生物相容性。在正常生理功能恢复后，血管会进行重建并降解。由于它不会长时间留在体内，患者也无需一直服用抗排斥药物，因此成为冠心病治疗中的关注焦点。本文介绍了可生物降解支架的发展历程，回顾了几种不同材料的血管支架（动物或人体）的研究现状，并指出了存在的问题。同时还预测了可生物降解血管支架的研究方向。
