Gallotti R, Semeraro F, Mamolo G, Casucci R, Grossi C, Ornaghi D, Panisi P, Tarelli G, Respighi E
Ospedale Multizonale, Varese, Divisione di Cardiochirurgia.
G Ital Cardiol. 1987 Oct;17(10):846-50.
Immediate coronary artery bypass for acute evolving myocardial infarction could be the elective therapy if provided on useful time, because myocardial salvage can be achieved by early reperfusion. Thirty eight patients had emergency coronary artery by-pass graft for acute evolving myocardial infarction during the early phase: 35 were male, the mean age was 51 years (34 to 74). The mean interval between the onset of symptoms and surgery in this series of patients was two hours and a half. This interval seems to be also the time limit in our experience to get a partial or complete recovery of ischemic area. Four patients died in hospital, but they were in severe cardiogenic shock before emergency surgery. Twenty nine cases were free of symptoms at a mean follow-up of 18 months (6 to 36) and two suffered for residual angina. Three patients died after discharge few months later: two during redo emergency vein grafts operations, one in deep left ventricular failure, while he was waiting for heart transplant. All these patients operated on as emergency developed acute myocardial infarction during their stay in hospital waiting for catheter study, surgical operation or during percutaneous transluminal coronary angioplasty. Saphenous vein grafts, were used in twenty nine patients, left internal mammary artery in nine cases, single in four and associated to saphenous vein in five, with an average number of anastomoses of 2.6 (1 to 6) for patient. ECG was found to be normal in 76% of the patients operated on within two hours and a half from the beginning of symptoms.(ABSTRACT TRUNCATED AT 250 WORDS)
对于急性进展期心肌梗死,若能在有效时间内进行即刻冠状动脉搭桥术,可作为选择性治疗方法,因为早期再灌注可实现心肌挽救。38例患者在急性期因急性进展期心肌梗死接受了急诊冠状动脉搭桥术:35例为男性,平均年龄51岁(34至74岁)。这组患者症状发作至手术的平均间隔时间为两个半小时。根据我们的经验,这段间隔时间似乎也是使缺血区域部分或完全恢复的时间限制。4例患者在医院死亡,但他们在急诊手术前已处于严重的心源性休克状态。29例患者在平均18个月(6至36个月)的随访中无症状,2例有残余心绞痛。3例患者在出院数月后死亡:2例在再次急诊静脉搭桥手术期间死亡,1例在等待心脏移植时死于严重的左心室衰竭。所有这些接受急诊手术的患者在住院等待导管检查、手术或经皮冠状动脉腔内血管成形术期间均发生了急性心肌梗死。29例患者使用了大隐静脉移植,9例使用了左乳内动脉,4例单独使用,5例与大隐静脉联合使用,每位患者的平均吻合口数量为2.6个(1至6个)。在症状发作后两个半小时内接受手术的患者中,76%的患者心电图恢复正常。(摘要截取自250字)