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An invasive procedure for in utero fetal electrocardiology: recording of fetal electrocardiograms by applying electrodes through the uterus.

作者信息

Williams H B, Rankin J S, Hamlin R L

出版信息

Am J Vet Res. 1978 Jan;39(1):183-4.

PMID:343665
Abstract

An in utero technique was developed that allows direct access to the canine fetus for experimentation. This procedure reduces the need for fetal manipulation and umbilical blood flow compromise and reduces fetal fluid loss. In pregnant bitches, uterine horns could be delivered through a ventral midline incision. By manipulating the fetal membranes, and positioning the fetuses through them, electrodes could be inserted subcutaneously in the fetuses. Electrocardiograms satisfactory for interpretation were obtained from as many as 4 fetuses in a bitch for periods up to postoperative week 3.

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