Cathcart-Rake W, Bone R C, Sobonya R E, Stephens R L
Am Rev Respir Dis. 1978 Mar;117(3):587-93. doi: 10.1164/arrd.1978.117.3.587.
A 24-year-old man with documented histiocytic lymphoma developed a nodular interstitial infiltrate, as shown by chest roentgenograms during a 10-day period of observation. He also developed fever, chills, and purulent sputum. Open-lung biopsy revealed histiocytic lymphoma without evidence of infection. This case demonstrates that lymphoma can cause rapid development of infiltrates observable by roentgenography. Because the infiltrate could be neoplastic or infectious, empiric therapy without an exact diagnosis is not warranted.
一名确诊为组织细胞性淋巴瘤的24岁男性，在为期10天的观察期内，胸部X线片显示出现了结节性间质浸润。他还出现了发热、寒战和脓性痰。开胸肺活检显示为组织细胞性淋巴瘤，无感染证据。该病例表明，淋巴瘤可导致X线可观察到的浸润迅速发展。由于浸润可能是肿瘤性的或感染性的，因此在没有确切诊断的情况下进行经验性治疗是不合理的。
