Sauer M V, Bustillo M, Rodi I A, Gorrill M J, Buster J E
Department of Obstetrics and Gynecology, Harbor-UCLA Medical Center, Torrance.
Hum Reprod. 1987 Nov;2(8):701-3. doi: 10.1093/oxfordjournals.humrep.a136617.
We evaluated ova recovered from 13 fertile women undergoing uterine lavage for purposes of embryo donation, and assessed differences in blastocyst production and ovum yield among subjects. Six women produced 10 blastocysts during 31 insemination cycles (32%). Yet, despite undergoing at least four insemination cycles apiece, seven women produced no blastocysts in 52 lavage attempts. Comparing the ovum recovery rates between the blastocyst-producing and non-blastocyst-producing groups, we found the former more likely to yield ova (P less than or equal to 0.05), and more importantly 10 to 20 recovered ova were blastocysts. We conclude that donor fecundity is highly variable among fertile women, and that reproductive history alone does not predict ovum donor efficiency.
我们评估了13名接受子宫灌洗以进行胚胎捐赠的育龄女性所回收的卵子，并评估了受试者之间囊胚生成和卵子产量的差异。6名女性在31个授精周期中产生了10个囊胚（32%）。然而，尽管每位女性至少经历了4个授精周期，但7名女性在52次灌洗尝试中未产生囊胚。比较产生囊胚组和未产生囊胚组的卵子回收率，我们发现前者更有可能产生卵子（P小于或等于0.05），更重要的是，回收的10至20个卵子为囊胚。我们得出结论，育龄女性的供体生育力差异很大，仅生殖史并不能预测卵子捐赠效率。
