Department of Molecular and Translational Science, Monash University, Clayton 3168, Australia.
Department of Life Sciences, School of Pharmacy, International Medical University (IMU), Kuala Lumpur 57000, Malaysia.
Viruses. 2021 Jul 18;13(7):1397. doi: 10.3390/v13071397.
The recent coronavirus disease 2019 (COVID-19) outbreak has drawn global attention, affecting millions, disrupting economies and healthcare modalities. With its high infection rate, COVID-19 has caused a colossal health crisis worldwide. While information on the comprehensive nature of this infectious agent, SARS-CoV-2, still remains obscure, ongoing genomic studies have been successful in identifying its genomic sequence and the presenting antigen. These may serve as promising, potential therapeutic targets in the effective management of COVID-19. In an attempt to establish herd immunity, massive efforts have been directed and driven toward developing vaccines against the SARS-CoV-2 pathogen. This review, in this direction, is aimed at providing the current scenario and future perspectives in the development of vaccines against SARS-CoV-2.
最近爆发的 2019 年冠状病毒病（COVID-19）引起了全球关注，影响了数百万人，扰乱了经济和医疗模式。由于其高感染率，COVID-19 在全球范围内造成了巨大的健康危机。虽然有关这种传染性病原体 SARS-CoV-2 的全面性质的信息仍然不清楚，但正在进行的基因组研究成功地确定了其基因组序列和呈现的抗原。这些可能成为 COVID-19 有效管理的有前途的潜在治疗靶点。为了建立群体免疫，人们已经做出了巨大的努力来开发针对 SARS-CoV-2 病原体的疫苗。本综述旨在提供针对 SARS-CoV-2 疫苗开发的现状和未来展望。
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