Swerts A, Evers-Kiebooms G, Van den Berghe H
Center for Human Genetics, University of Leuven.
J Genet Hum. 1987 Dec;35(5):339-49.
Ninety-four mothers who had been in contact with the Center for Human Genetics of the University of Leuven (Belgium) after the birth of a child with neural tube defect were questioned about the outcomes of their pregnancies. To this end a structured interview and a mailed questionnaire were used. The recurrence rate for neural tube defects after the birth of one affected child was 2.9%. This number is at the lower border of the risk rates (between 3% and 5%) generally given to parents during genetic counseling sessions. The relative amount of miscarriages was larger in the interviewed group than in the Belgian population in general.
94名在孩子出生后与比利时鲁汶大学人类遗传学中心有过接触的母亲被询问了她们的妊娠结局。为此，采用了结构化访谈和邮寄问卷的方式。一个孩子患神经管缺陷出生后，神经管缺陷的复发率为2.9%。这个数字处于遗传咨询期间通常告知父母的风险率（3%至5%）的下限。接受访谈的群体中流产的相对数量高于比利时总体人群。
