Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Department of Respiratory Medicine, National Hospital Organization Utsunomiya National Hospital, Japan.
Intern Med. 2022 Feb 15;61(4):523-526. doi: 10.2169/internalmedicine.8074-21. Epub 2021 Aug 6.
We herein report the long-term changes in chest computed tomography (CT) findings from early sarcoidosis lesions to pleuroparenchymal fibroelastosis (PPFE)-like lesions in a 30-year-old man with granulomas on a transbronchial lung biopsy. Multiple bilateral micronodular and nodular opacities around the bronchovascular bundle in the upper lobes detected by chest CT in 2004 disappeared, but paradoxically, peripheral consolidations continued to grow at the periphery of the original lesions. Chest CT in 2017 confirmed the progression of bilateral shrinkage of the upper lobe, spread of peripheral consolidations and wedge-shaped opacities below the first rib, and bronchiectatic air bronchograms, confirming PPFE-like lesions.
我们在此报告一例 30 岁男性患者，其支气管肺活检显示肉芽肿，经胸部 CT 检查发现早期结节病病变的长期变化，出现胸膜肺弹力纤维增生（PPFE）样病变。2004 年胸部 CT 显示多个双侧肺门血管束周围微结节和结节状阴影，2017 年胸部 CT 显示双侧上叶进行性收缩，外周实变和第一肋下楔形阴影扩展，支气管扩张性空气支气管征，证实为 PPFE 样病变。
