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“我选择了人迹罕至的道路,这使一切变得不同”:在新诊断为多发性骨髓瘤的老年患者中提倡采用大剂量化疗和自体干细胞移植。

"I took the road less traveled, and that has made all the difference": Making a case for high-dose therapy and autologous stem cell transplantation in elderly patients with newly diagnosed multiple myeloma.

机构信息

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.

出版信息

Cancer. 2021 Nov 15;127(22):4133-4136. doi: 10.1002/cncr.33825. Epub 2021 Aug 10.

DOI:10.1002/cncr.33825
PMID:34374440
Abstract

Elderly patients with myeloma derive benefits from transplantation similar to those for younger patients. Age should not be the sole criterion for determining transplant eligibility. Performance status assessment and other tools for assessing comorbidities such as the Charlson comorbidity score may potentially help in determining transplant eligibility and will allow us to move away from our heavy reliance on numerical age.

摘要

老年骨髓瘤患者从移植中获得的益处与年轻患者相似。年龄不应是决定移植资格的唯一标准。体能状态评估和其他用于评估合并症的工具,如 Charlson 合并症评分,可能有助于确定移植资格,并使我们摆脱对数字年龄的过度依赖。

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Front Oncol. 2022 Mar 9;12:830922. doi: 10.3389/fonc.2022.830922. eCollection 2022.