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脑损伤问题的一个重要新维度。

A major new dimension in the problem of brain injury.

机构信息

National Center for Adaptive Neurotechnologies, Albany Stratton VA Medical Center, Albany, United States.

Albany Stratton VA Medical Center, Albany, United States.

出版信息

Elife. 2021 Aug 10;10:e72048. doi: 10.7554/eLife.72048.

DOI:10.7554/eLife.72048
PMID:34374646
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8354631/
Abstract

Evidence that neurohormones contribute to the contralateral effects of unilateral brain injury challenges a fundamental assumption of basic neuroscience and clinical neurology.

摘要

神经激素有助于单侧脑损伤的对侧效应，这一证据对基础神经科学和临床神经学的一个基本假设提出了挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76bb/8354631/55beadb0a43e/elife-72048-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76bb/8354631/55beadb0a43e/elife-72048-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76bb/8354631/55beadb0a43e/elife-72048-fig1.jpg

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Left-right side-specific endocrine signaling complements neural pathways to mediate acute asymmetric effects of brain injury.左右侧特异性内分泌信号补充神经通路，介导脑损伤的急性非对称效应。
Elife. 2021 Aug 10;10:e65247. doi: 10.7554/eLife.65247.
2
Left-Right Side-Specific Neuropeptide Mechanism Mediates Contralateral Responses to a Unilateral Brain Injury.左右侧特定神经肽机制介导单侧脑损伤的对侧反应。
eNeuro. 2021 May 25;8(3). doi: 10.1523/ENEURO.0548-20.2021. Print 2021 May-Jun.
3
Rudimentary Dexterity Corresponds With Reduced Ability to Move in Synergy After Stroke: Evidence of Competition Between Corticoreticulospinal and Corticospinal Tracts?
基本动作灵巧性与中风后协同运动能力下降有关：皮质网状脊髓束和皮质脊髓束之间存在竞争的证据？
Neurorehabil Neural Repair. 2020 Oct;34(10):904-914. doi: 10.1177/1545968320943582. Epub 2020 Aug 24.
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Lateralized kappa opioid receptor signaling from the amygdala central nucleus promotes stress-induced functional pain.杏仁中央核的偏侧化 κ 阿片受体信号促进应激诱导的功能性疼痛。
Pain. 2018 May;159(5):919-928. doi: 10.1097/j.pain.0000000000001167.
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Intra- and interregional coregulation of opioid genes: broken symmetry in spinal circuits.阿片类基因的区域内和区域间共同调节：脊髓回路中的对称性破坏
FASEB J. 2017 May;31(5):1953-1963. doi: 10.1096/fj.201601039R. Epub 2017 Jan 25.
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Oxytocin enables maternal behaviour by balancing cortical inhibition.催产素通过平衡皮质抑制来实现母性行为。
Nature. 2015 Apr 23;520(7548):499-504. doi: 10.1038/nature14402. Epub 2015 Apr 15.
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Asymmetry of the endogenous opioid system in the human anterior cingulate: a putative molecular basis for lateralization of emotions and pain.人类前扣带中内源性阿片系统的不对称性：情绪和疼痛偏侧化的一种假定分子基础。
Cereb Cortex. 2015 Jan;25(1):97-108. doi: 10.1093/cercor/bht204. Epub 2013 Aug 19.
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