Cancer Cell. 2021 Aug 9;39(8):1015-1017. doi: 10.1016/j.ccell.2021.07.009.
Tumor heterogeneity was traditionally considered in the genetic terms, but it has now been broadened into many more facets. These facets represent a challenge in our understanding of cancer etiology but also provide opportunity for us to understand prognosis and therapy response.
肿瘤异质性传统上被认为是遗传上的,但现在已经扩展到更多的方面。这些方面不仅代表了我们对癌症病因学理解的挑战,也为我们提供了了解预后和治疗反应的机会。