Kumar M Senthil, Kalimuthu M, Selvam A, Mathivanan A, Paramasivan R, Kumar Ashwani, Gupta Bhavna
ICMR-Vector Control Research Center, 4, Sarojini Street Chinna Chokkikulam, Madurai 625002, India.
ICMR-Vector Control Research Center, Medical Complex, Indira Nagar, 605006 Puducherry, India.
Infect Genet Evol. 2021 Nov;95:105031. doi: 10.1016/j.meegid.2021.105031. Epub 2021 Aug 8.
We investigated the genetic variability and differentiation among 12 Ae. aegypti populations collected within the Madurai city in Tamil Nadu state of Southern India. Genotyping of 12 microsatellite markers in 353 individual samples showed moderate levels of genetic diversity among 12 populations. UPGMA tree, hierarchical clustering, Bayesian clustering and Discriminant Analysis on Principal Components roughly divided these populations into two genetic clusters: main city populations and the populations located at the border of the corporation limit. Significant positive correlation between genetic and geographic distance was observed among 12 populations, however, the correlation was non-significant within each genetic cluster. Population assignment and divMigrate graph depicted less migration between two groups. Overall, the findings of this study provided an overview of Ae. aegypti population structure within an urban setting in India that have implications in effective implementation of vector control in the city area.
我们调查了在印度南部泰米尔纳德邦马杜赖市采集的12个埃及伊蚊种群的遗传变异性和分化情况。对353个个体样本中的12个微卫星标记进行基因分型，结果显示12个种群之间存在中等水平的遗传多样性。UPGMA树、层次聚类、贝叶斯聚类和主成分判别分析大致将这些种群分为两个遗传簇：主要城市种群和位于市政当局边界的种群。在12个种群之间观察到遗传距离与地理距离之间存在显著正相关，然而，在每个遗传簇内这种相关性并不显著。种群分配和divMigrate图显示两组之间的迁移较少。总体而言，本研究结果概述了印度城市环境中埃及伊蚊的种群结构，这对在城市地区有效实施病媒控制具有重要意义。
