支气管内超声引导下经支气管针吸活检术在孤立性纵隔肿物诊断中的实用性与安全性
Utility and Safety of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in the Diagnosis of Isolated Mediastinal Masses.
作者信息
Pan Feng, Lu Ai-Ting, Mao Xiaowei, Chen Yefeng, Zhao Yizhuo, Han Baohui
机构信息
Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, People's Republic of China.
Department of Nursing, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, People's Republic of China.
出版信息
J Multidiscip Healthc. 2021 Aug 3;14:2047-2052. doi: 10.2147/JMDH.S317060. eCollection 2021.
BACKGROUND
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a valuable tool for diagnosing pulmonary disease due to its efficiency and safety. We retrospectively analyzed patients with mediastinal masses who underwent diagnostic EBUS-TBNA at Shanghai Chest Hospital, and evaluated the clinical accuracy of EBUS-TBNA in the diagnosis mediastinal masses.
METHOD
From 2009 and 2014, patients who received EBUS-TBNA to diagnose a isolated mediastinal mass were enrolled. Clinical follow-up was performed to ascertain the patient's final diagnosis.
RESULTS
Forty-six patients were enrolled in this study. Thirty-seven were diagnosed with an oncologic disease, 3 were diagnosed with a mediastinal infection, and 2 were found to have a mediastinal goiter. The overall sensitivity, specificity, positive predictive value, negative predictive value, diagnostic yield was 63.6%, 100%, 100%, 42.9%, and 71.4%, respectively.
CONCLUSION
EBUS-TBNA is a safe and effective means of diagnosing mediastinal masses.
背景
由于其有效性和安全性，支气管内超声引导下经支气管针吸活检术（EBUS-TBNA）是诊断肺部疾病的一种有价值的工具。我们回顾性分析了在上海胸科医院接受诊断性EBUS-TBNA的纵隔肿块患者，并评估了EBUS-TBNA在诊断纵隔肿块中的临床准确性。
方法
纳入2009年至2014年期间接受EBUS-TBNA诊断孤立性纵隔肿块的患者。进行临床随访以确定患者的最终诊断。
结果
本研究共纳入46例患者。37例被诊断为肿瘤性疾病，3例被诊断为纵隔感染，2例发现有纵隔甲状腺肿。总体敏感性、特异性、阳性预测值、阴性预测值、诊断率分别为63.6%、100%、100%、42.9%和71.4%。
结论
EBUS-TBNA是诊断纵隔肿块的一种安全有效的方法。
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