Li Jun, Wang Yanling, Xiao Yan, Bai Fang, Xie Hai, Wang Keng, Huang Xiangmei, Wang Li'na, Shen Jing, Zhou Yu, Cai Xiuyu, Lu Bing
Endoscopic Center, The First Affiliated Hospital of Hainan Medical University Haikou, Hainan Province, China.
Department of Oncology, The First Affiliated Hospital of Hainan Medical University Haikou, Hainan Province, China.
Am J Transl Res. 2021 Jul 15;13(7):8471-8479. eCollection 2021.
To determine the effect of different preoperative fasting time on safety and postoperative complications of painless gastrointestinal endoscopy for polyps in patients.
Enrolled patients were assigned to an observation group and a control group by the random number table method (each n=68). Before operation, each patient in the observation group was fasted from solids for 6 h and from liquids for 2 h, while each one in the control group was fasted from solids for 8-12 h and from liquids for 4 h according to the conventional method. The levels of blood glucose, insulin, potassium and sodium in patients before and after operation were determined, and their hunger and thirst were recorded before anesthesia. Additionally, the incidences and degrees of vomiting and nausea among the patients after anesthesia and operation were recorded.
Before operation, the observation group showed higher levels of blood glucose, insulin, serum potassium and serum sodium than the control group (all P<0.001), while after operation, the observation group showed lower levels of blood glucose and insulin and higher levels of serum potassium and serum sodium than the control group (all P<0.001). In addition, the degrees and incidences of hunger and thirst in patients of the observation group were significantly lower than those in the control group before operation (P<0.01), and the degrees and incidences of nausea and vomiting in the observation group were also notably lower than those in the control group before and after operation (both P<0.05).
For patients undergoing painless gastrointestinal endoscopy for polyps, shortening their fasting time from solids and liquids before operation can stabilize their blood glucose, insulin and electrolyte levels before and after operation, relieve their thirst and hunger before operation, and reduce the incidences of postoperative nausea and vomiting.
探讨不同术前禁食时间对无痛胃肠镜息肉切除术患者安全性及术后并发症的影响。
采用随机数字表法将纳入的患者分为观察组和对照组（每组n = 68）。术前，观察组患者固体食物禁食6小时、液体禁食2小时，对照组患者按传统方法固体食物禁食8 - 12小时、液体禁食4小时。测定患者术前、术后血糖、胰岛素、钾、钠水平，记录麻醉前患者饥饿和口渴情况。此外，记录麻醉及术后患者呕吐、恶心的发生率及程度。
术前，观察组血糖、胰岛素、血钾、血钠水平高于对照组（均P < 0.001）；术后，观察组血糖、胰岛素水平低于对照组，血钾、血钠水平高于对照组（均P < 0.001）。此外，观察组患者术前饥饿和口渴程度及发生率显著低于对照组（P < 0.01），观察组麻醉前后恶心、呕吐程度及发生率也显著低于对照组（均P < 0.05）。
对于接受无痛胃肠镜息肉切除术的患者，缩短术前固体食物和液体的禁食时间可稳定其手术前后的血糖、胰岛素及电解质水平，缓解术前口渴和饥饿，并降低术后恶心、呕吐的发生率。
