Chamroensakchai Tamonwan, Kanjanabuch Talerngsak, Saikong Wadsamon, Panya Worauma, Thaweekote Siriwan, Eiam-Ong Somchai, Hurdeal Vedprakash G, Hyde Kevin D
Center of Excellence in Kidney Metabolic Disorders, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Med Mycol Case Rep. 2021 Jul 13;33:26-29. doi: 10.1016/j.mmcr.2021.06.005. eCollection 2021 Sep.
This is the first human infection caused by , resulting in peritonitis in a patient on peritoneal dialysis initially diagnosed as sterile peritonitis, resulting in delayed diagnosis and treatment. This pathogen posed a challenging diagnosis, causing low-grade peritonitis and difficulty to culture with standard bacterial broth. Moreover, automated platforms for pathogenic yeast identification could not specify the species, but broad-range PCR targeting rDNA followed by DNA sequencing successfully solved the etiology.
这是由……引起的首例人类感染,导致一名接受腹膜透析的患者发生腹膜炎,最初被诊断为无菌性腹膜炎,从而造成诊断和治疗延误。这种病原体的诊断颇具挑战性,引发了低度腹膜炎,且难以用标准细菌培养液培养。此外,致病性酵母鉴定的自动化平台无法明确其种类,但针对核糖体DNA的广谱聚合酶链反应(PCR)随后进行DNA测序成功解决了病因问题。