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触及不可及之处:难治性阿片类药物成瘾患者丙型肝炎病毒根除策略——一项真实世界经验

Reaching the Unreachable: Strategies for HCV Eradication in Patients With Refractory Opioid Addiction-A Real-world Experience.

作者信息

Sandmann Lisa, Deppe Julian, Beier Christoph, Ohlendorf Valerie, Schneider Julia, Wedemeyer Heiner, Wedegärtner Felix, Cornberg Markus, Maasoumy Benjamin

机构信息

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.

出版信息

Open Forum Infect Dis. 2021 Jun 17;8(8):ofab325. doi: 10.1093/ofid/ofab325. eCollection 2021 Aug.

DOI:10.1093/ofid/ofab325
PMID:34377724
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8339280/
Abstract

To achieve global hepatitis C virus (HCV) eradication, barriers prohibiting treatment access need to be overcome. We established a strategy to initiate antiviral therapy in patients with severe, refractory heroin addiction. All patients achieved sustained virological response. Outreach programs of hepatologists might be a reasonable way to overcome barriers to HCV treatment.

摘要

为实现全球丙型肝炎病毒(HCV)的根除,必须克服阻碍治疗可及性的障碍。我们制定了一项策略,对患有严重难治性海洛因成瘾的患者启动抗病毒治疗。所有患者均实现了持续病毒学应答。肝病专家的外展项目可能是克服HCV治疗障碍的合理方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3a1/8339280/4c6ee6d1dd37/ofab325f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3a1/8339280/4c6ee6d1dd37/ofab325f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3a1/8339280/4c6ee6d1dd37/ofab325f0001.jpg

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HCV micro-elimination in individuals with HIV in the Netherlands 4 years after universal access to direct-acting antivirals: a retrospective cohort study.荷兰在普遍获得直接作用抗病毒药物治疗 4 年后消除 HIV 合并 HCV 感染个体:一项回顾性队列研究。
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