Roe Chandler C, Urbanz Jennifer, Andrews Lela, Verocai Guilherme G, Engelthaler David M, Hepp Crystal M, Sahl Jason W
The Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ, USA.
Translational Genomics Research Institute, Flagstaff, AZ, USA.
Mitochondrial DNA B Resour. 2021 Aug 5;6(9):2572-2574. doi: 10.1080/23802359.2021.1960211. eCollection 2021.
Rodonaja 1967, is an emerging, zoonotic filarial nematode parasite that causes ocular disease in dogs, cats, wild canids, and humans. It is the causative agent of ocular onchocercosis in canines with increasing incidence in both North America and the Old World during the early twenty-first century. We report the complete mitochondrial genome of an isolate from a dog from Arizona, southwestern USA, and its genetic differentiation from related species. The whole mitochondrial genome was obtained from whole genome sequencing of genomic DNA isolated from an adult worm. This mitogenome is 13,766 bp in size and contains 36 genes and a control region. This mitogenome provides a valuable resource for future studies involving epidemiological surveillance, population genetics, phylogeography, and comparative mitogenomics of this emerging pathogen and other parasitic nematodes.
罗多纳贾线虫(Rodonaja)于1967年被发现,是一种新出现的人兽共患丝虫线虫寄生虫,可导致犬、猫、野生犬科动物和人类出现眼部疾病。它是犬类眼部盘尾丝虫病的病原体,在21世纪初,北美和旧世界的发病率都在上升。我们报告了从美国西南部亚利桑那州一只狗身上分离出的一个菌株的完整线粒体基因组,以及它与相关物种的遗传分化情况。完整的线粒体基因组是通过对从一条成虫分离出的基因组DNA进行全基因组测序获得的。这个有丝分裂基因组大小为13766 bp,包含36个基因和一个控制区。这个有丝分裂基因组为未来涉及这种新出现病原体及其他寄生线虫的流行病学监测、群体遗传学、系统地理学和比较有丝分裂基因组学的研究提供了宝贵资源。