Department of Obstetrics and Gynecology, Kitano Hospital, Osaka, Japan.
Department of Obstetrics and Gynecology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
J Obstet Gynaecol Res. 2021 Nov;47(11):4093-4100. doi: 10.1111/jog.14969. Epub 2021 Aug 10.
Lymphoepithelioma-like carcinoma of the uterine cervix is a rare variant of squamous cell carcinoma. Herein, we describe three cases of lymphoepithelioma-like carcinoma of the uterine cervix and review relevant literature. All three patients initially presented with postmenopausal bleeding. Gross appearances were endophytic with ulcerated mucosa in case 1, exophytic with polypoid morphology in case 2, and unremarkable even using colposcopy and hysteroscopy in case 3. Magnetic resonance imaging demonstrated well-demarcated cervical masses with high-intermediate intensity on T2-weighted images and high intensity on diffusion-weighted images in all three cases. In case 3, biopsy referring to local information from magnetic resonance images was required for preoperative diagnosis. We reviewed the literature of 59 lymphoepithelioma-like carcinoma cases in 19 papers published between 2001 and 2020. Preoperative diagnosis of lymphoepithelioma-like carcinoma is sometimes challenging, although magnetic resonance imaging findings may help determine the location of the tumor and obtain a successful biopsy.
宫颈淋巴上皮样癌是一种罕见的鳞状细胞癌变异型。本文描述了 3 例宫颈淋巴上皮样癌病例，并复习相关文献。所有 3 例患者最初均表现为绝经后出血。大体外观上，1 例为内生型，伴溃疡状黏膜；2 例为外生型，呈息肉样形态；3 例阴道镜和宫腔镜检查未见明显异常。3 例患者的磁共振成像（MRI）均显示边界清楚的宫颈肿块，T2 加权像呈中高信号，弥散加权成像呈高信号。3 例患者均需要根据 MRI 局部信息进行术前活检以明确诊断。本文复习了 2001 年至 2020 年 19 篇文献中报道的 59 例宫颈淋巴上皮样癌病例。尽管 MRI 检查结果可能有助于确定肿瘤的位置并获得成功的活检，但宫颈淋巴上皮样癌的术前诊断有时仍具有挑战性。
