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COVID-19 阳性儿科实体器官移植受者的临床结局和抗体反应。

Clinical Outcomes and Antibody Response in COVID-19-Positive Pediatric Solid Organ Transplant Recipients.

机构信息

From the Department of Pediatrics, Assuta Ashdod University Hospital, Ashdod, Israel.

Institute of Gastroenterology, Nutrition, and Liver Disease.

出版信息

Pediatr Infect Dis J. 2021 Dec 1;40(12):e514-e516. doi: 10.1097/INF.0000000000003293.

Abstract

We describe the clinical and laboratory manifestations and outcomes of 25 pediatric solid organ transplant recipients who tested positive for severe acute respiratory coronavirus-2. Twenty-one (84%) developed a mild disease; 22 of 23 (96%) had a positive serologic response. Two patients (8%), both kidney transplant recipients with additional comorbidities, developed a severe disease. The findings emphasize the need for close monitoring of this population.

摘要

我们描述了 25 名接受过儿科实体器官移植的患者,他们的严重急性呼吸冠状病毒-2 检测呈阳性。21 名(84%)患者出现轻度疾病;23 名患者中的 22 名(96%)具有阳性血清学反应。两名患者(8%)均为患有其他合并症的肾移植受者,发展为严重疾病。这些发现强调了需要对这一人群进行密切监测。

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本文引用的文献

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COVID-19 in pediatric kidney transplantation: The Improving Renal Outcomes Collaborative.
Am J Transplant. 2021 Aug;21(8):2740-2748. doi: 10.1111/ajt.16501. Epub 2021 Feb 11.
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Testing IgG antibodies against the RBD of SARS-CoV-2 is sufficient and necessary for COVID-19 diagnosis.
PLoS One. 2020 Nov 23;15(11):e0241164. doi: 10.1371/journal.pone.0241164. eCollection 2020.
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