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建立参考区间和中位数倍数(MoM)的重要性。

Importance of Setting Up Reference Intervals and Multiple of Medians (MoM).

机构信息

Department of Biochemistry, Raipur, All India Institute of Medical Sciences, Chhattisgarh, India.

出版信息

Horm Metab Res. 2021 Sep;53(9):633. doi: 10.1055/a-1432-2225. Epub 2021 Aug 12.

DOI:10.1055/a-1432-2225
PMID:34384103
Abstract

I was interested in the article of Kianpour et al. on reference intervals for thyroid hormones during the first trimester of gestation from an area with sufficient iodine level 1. The unavailability of data in this population had triggered this study where 436 pregnant and 444 non-pregnant women were recruited. I appreciate the great effort taken by the authors to recruit such a large population for the study. Following screening as per exclusion criteria 291 pregnant women were eliminated and thus the data of 145 pregnant was included for analysis. However, the article mentions the analysis of samples of 185 patients. The authors have also calculated the multiples of medians (MoM) to unitise different laboratory reports.

摘要

我对 Kianpour 等人在碘充足地区妊娠早期甲状腺激素参考区间的文章很感兴趣。1 该人群缺乏数据,因此开展了这项研究,共招募了 436 名孕妇和 444 名非孕妇。我赞赏作者为这项研究招募如此庞大的人群所付出的巨大努力。经过按排除标准 2 进行筛查,排除了 291 名孕妇,因此纳入了 145 名孕妇的数据进行分析。然而,文章提到分析了 185 名患者的样本。作者还计算了中位数倍数 (MoM) 来统一不同实验室的报告。

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