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COVID-19 患者持续性呼吸衰竭中机化性肺炎的辅助皮质类固醇治疗。

Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure.

机构信息

Infectious Diseases Unit, Catholic University of the Sacred Heart, Rome, Italy.

Unità Operativa Complessa di Pneumologia, Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy.

出版信息

Respir Med. 2021 Oct;187:106571. doi: 10.1016/j.rmed.2021.106571. Epub 2021 Aug 10.

Abstract

Since the beginning of COVID-19 pandemic, clinical, radiological and histopathological features consistent with viral-induced organizing pneumonia (OP) have been reported as hallmark characteristics of the disease. Here, we describe the case of ten patients with severe COVID-19 pneumonia treated with methylprednisolone 1mg/kg for showing clinical and radiological features suggestive of OP at least 20 days after symptom onset and despite standard treatment for COVID-19.

摘要

自 COVID-19 大流行开始以来,与病毒引起的机化性肺炎(OP)一致的临床、放射学和组织病理学特征已被报道为该疾病的特征性表现。在这里,我们描述了 10 例重症 COVID-19 肺炎患者的病例,这些患者在症状出现后至少 20 天出现了 OP 的临床和放射学特征,尽管对 COVID-19 进行了标准治疗,但仍使用了 1mg/kg 的甲基强的松龙进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1452/8352674/c1157d8ed8a9/gr1_lrg.jpg

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