Opt Lett. 2021 Aug 15;46(16):4009-4012. doi: 10.1364/OL.435166.
In this Letter, we report a study on the effects of spatial filtering for a transmission Mueller matrix imaging system. A spatial filter (SF) is placed on the back Fourier plane of the imaging lens in a dual-rotating-retarders Mueller matrix imaging system to select photons within a certain scattering angle. The system is then applied to three types of human cancerous tissues. When imaging with a small-aperture SF, some polarimetry basis parameters show sharp changes in contrast in the cancerous regions. Monte Carlo simulations using a simple sphere-cylinder scattering model also show that spatial filtering of the scattered photons provides extra information on the size and shape of the scattering particles. The results indicate that spatial filtering enhances the capability of polarization imaging as a powerful tool for biomedical diagnosis.
在这封信件中，我们报告了一项关于传输 Mueller 矩阵成像系统中空间滤波效果的研究。在双旋转延迟 Mueller 矩阵成像系统中，在成像透镜的后傅立叶平面上放置一个空间滤波器 (SF)，以选择一定散射角内的光子。然后将该系统应用于三种类型的人类癌组织。当使用小孔径 SF 进行成像时，某些偏振度基础参数在癌组织区域显示出对比度的急剧变化。使用简单的球-柱散射模型的蒙特卡罗模拟也表明，对散射光子进行空间滤波可提供有关散射粒子的大小和形状的额外信息。结果表明，空间滤波增强了偏振成像作为生物医学诊断的有力工具的能力。
