Carman R J, van Tassell R L, Wilkins T D
Department of Anaerobic Microbiology, Virginia Polytechnic Institute and State University, Blacksburg 24061.
Vet Microbiol. 1987 Oct;15(1-2):115-20. doi: 10.1016/0378-1135(87)90136-2.
The effects of divalent cations (Ca2+, Co2+ and Zn2+) on the production of iota toxin by Clostridium spiroforme were studied. Toxin production had an absolute requirement for one or more cations in the range 1-5 mM. Using bispecific antisera, we showed that production of both the components of the toxin (ia and ib) were enhanced by divalent cations added to brain-heart infusion supplemented with peptone and glucose.
研究了二价阳离子（Ca2+、Co2+和Zn2+）对螺旋形梭菌产生埃塔毒素的影响。毒素产生绝对需要1-5 mM范围内的一种或多种阳离子。使用双特异性抗血清，我们发现添加到补充有蛋白胨和葡萄糖的脑心浸液中的二价阳离子可增强毒素两种成分（ia和ib）的产生。
