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快速序贯器官衰竭评估(QSIRS)可提高快速序贯器官衰竭评分(QSOFA)和全身炎症反应综合征(SIRS)预测外科急症死亡率的准确性。

QSIRS Can Improve Accuracy of QSOFA and SIRS in Prediction of Mortality in Surgical Emergencies.

作者信息

Ndong Abdourahmane, Diallo Adja Coumba, Tendeng Jacques Noel, Diallo Amadou Ibra, Diao Mohamed Lamine, Sagna Sylvain Assega, Diop Saer, Dia Diago Anta, Diouf Daouda, Racine Bayo Ismael, Nyemb Philippe Manyacka Ma, Konaté Ibrahima

机构信息

Department of Surgery, Gaston Berger University, Saint-Louis, Senegal.

Department of Public Health and Preventive Medicine, Cheikh Anta Diop University, Dakar, Senegal.

出版信息

Surg J (N Y). 2021 Aug 3;7(3):e199-e202. doi: 10.1055/s-0041-1733831. eCollection 2021 Jul.

Abstract

The quick sequential organ failure assessment (QSOFA) score and the systemic inflammatory response syndrome (SIRS) criteria were developed to predict the risk of sepsis and death in patients received in emergency. To improve sensitivity in predicting death, the association of the two scores was proposed under the term QSIRS (QSOFA + SIRS). Our aim was to determine the accuracy of QSOFA, SIRS, and QSIRS in prediction of mortality in surgical emergencies, and to compare these scores.  This is a prospective study over a period of 1 year. Patients older than 15 years who presented a digestive surgical emergency (bowel obstruction, peritonitis, appendicitis, strangulated hernia) were included. For each score, the specificity, the sensitivity, the positive predictive value, the negative predictive value, and areas under the receiver operating characteristic (ROC) curve (AUC) were compared.  One hundred and eighteen patients were included and 11 deaths were recorded (9.3%). There was a statistically significant relationship between each score and death (QSOFA  = 0.01, SIRS  = 0.003, and QSIRS  = 0.004). The realization of the ROC curve found a higher AUC for QSIRS (0.845 [0.767-0.905]) compared with QSOFA (0.783 [0.698-0.854]) and SIRS (0.737 [0.648-0.813]). QSIRS (90.9%) had a higher sensitivity compared with the two other scores alone (SIRS = 81.9% and QSOFA = 36.3%).  Our study found that QSIRS improves the ability to predict death in digestive surgical emergencies.

摘要

快速序贯器官衰竭评估(QSOFA)评分和全身炎症反应综合征(SIRS)标准旨在预测急诊患者发生脓毒症和死亡的风险。为提高预测死亡的敏感性,有人提出将这两种评分联合使用,称为QSIRS(QSOFA + SIRS)。我们的目的是确定QSOFA、SIRS和QSIRS在预测外科急诊患者死亡率方面的准确性,并比较这些评分。

这是一项为期1年的前瞻性研究。纳入年龄大于15岁、出现消化外科急诊(肠梗阻、腹膜炎、阑尾炎、绞窄性疝)的患者。比较每种评分的特异性、敏感性、阳性预测值、阴性预测值以及受试者工作特征(ROC)曲线下面积(AUC)。

共纳入118例患者,记录到11例死亡(9.3%)。每种评分与死亡之间均存在统计学显著关系(QSOFA = 0.01,SIRS = 0.003,QSIRS = 0.004)。绘制ROC曲线发现,与QSOFA(0.783 [0.698 - 0.854])和SIRS(0.737 [0.648 - 0.813])相比,QSIRS的AUC更高(0.845 [0.767 - 0.905])。与单独的其他两种评分相比(SIRS = 81.9%,QSOFA = 36.3%),QSIRS的敏感性更高(90.9%)。

我们的研究发现,QSIRS提高了预测消化外科急诊患者死亡的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/970e/8354340/1bd814e9e118/10-1055-s-0041-1733831-i2000071-1.jpg

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