Department of Surgery, University of Washington, Seattle, Washington, USA.
Br J Surg. 2014 Jan;101(1):e9-22. doi: 10.1002/bjs.9329. Epub 2013 Nov 25.
Surgical disease is inadequately addressed globally, and emergency conditions requiring surgery contribute substantially to the global disease burden.
This was a review of studies that contributed to define the population-based health burden of emergency surgical conditions (excluding trauma and obstetrics) and the status of available capacity to address this burden. Further data were retrieved from the Global Burden of Disease Study 2010 and the University of Washington's Institute for Health Metrics and Evaluation online data.
In the index year of 2010, there were 896,000 deaths, 20 million years of life lost and 25 million disability-adjusted life-years from 11 emergency general surgical conditions reported individually in the Global Burden of Disease Study. The most common cause of death was complicated peptic ulcer disease, followed by aortic aneurysm, bowel obstruction, biliary disease, mesenteric ischaemia, peripheral vascular disease, abscess and soft tissue infections, and appendicitis. The mortality rate was higher in high-income countries (HICs) than in low- and middle-income countries (LMICs) (24.3 versus 10.6 deaths per 100,000 inhabitants respectively), primarily owing to a higher rate of vascular disease in HICs. However, because of the much larger population, 70 per cent of deaths occurred in LMICs. Deaths from vascular disease rose from 15 to 25 per cent of surgical emergency-related deaths in LMICs (from 1990 to 2010). Surgical capacity to address this burden is suboptimal in LMICs, with fewer than one operating theatre per 100,000 inhabitants in many LMICs, whereas some HICs have more than 14 per 100,000 inhabitants.
The global burden of surgical emergencies is described insufficiently. The bare estimates indicate a tremendous health burden. LMICs carry the majority of emergency conditions; in these countries the pattern of surgical disease is changing and capacity to deal with the problem is inadequate. The data presented in this study will be useful for both the surgical and public health communities to plan a more adequate response.
全球范围内对手术相关疾病的重视程度不足,需要紧急手术的情况对全球疾病负担有很大影响。
这是一项对研究的综述,旨在确定紧急手术条件(不包括创伤和产科)的人群健康负担,并评估现有应对能力。进一步的数据来自 2010 年全球疾病负担研究和华盛顿大学健康计量和评估研究所的在线数据。
在 2010 年,全球疾病负担研究报告了 11 种紧急普通外科疾病,导致 89.6 万人死亡,2000 万年生命损失和 2500 万残疾调整生命年。最常见的死亡原因是复杂消化性溃疡病,其次是主动脉瘤、肠梗阻、胆道疾病、肠系膜缺血、周围血管疾病、脓肿和软组织感染以及阑尾炎。高收入国家(HICs)的死亡率高于中低收入国家(LMICs)(分别为每 10 万人 24.3 和 10.6 人死亡),主要是由于 HICs 血管疾病的发生率更高。然而,由于人口数量庞大,70%的死亡发生在 LMICs。血管疾病导致的死亡占 LMICs 手术急症相关死亡的比例从 1990 年的 15%上升到 2010 年的 25%。LMICs 处理这种负担的手术能力不足,许多 LMICs每 10 万人拥有不到一个手术室,而一些 HICs 每 10 万人拥有超过 14 个手术室。
全球紧急手术负担描述不足。仅有的估计表明存在巨大的健康负担。LMICs 承担了大部分紧急情况;在这些国家,手术疾病的模式正在发生变化,应对问题的能力不足。本研究提供的数据将对外科和公共卫生界规划更充分的应对措施非常有用。