Lenihan Daniel J, Fradley Michael G, Dent Susan, Brezden-Masley Christine, Carver Joseph, Filho Roberto Kalil, Neilan Tomas G, Blaes Anne, Melloni Chiara, Herrmann Joerg, Armenian Saro, Thavendiranathan Paaladinesh, Armstrong Gregory T, Ky Bonnie, Hajjar Ludhmila
Cardio-Oncology Center of Excellence, Cardiovascular Division, Department of Internal Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Cardio-Oncology Program, Moffitt Cancer Center, University of South Florida, Tampa, Florida, USA.
JACC CardioOncol. 2019 Dec 17;1(2):256-272. doi: 10.1016/j.jaccao.2019.11.007. eCollection 2019 Dec.
The discipline of cardio-oncology has expanded at a remarkable pace. Recent developments and challenges to clinicians who practice cardio-oncology were presented at the Global Cardio-Oncology Summit on October 3 to 4, 2019, in São Paulo, Brazil. Here, we present the top 10 priorities for our field that were discussed at the meeting, and also detail a potential path forward to address these challenges. Defining robust predictors of cardiotoxicity, clarifying the role of cardioprotection, managing and preventing thromboembolism, improving hematopoietic stem cell transplant outcomes, personalizing cardiac interventions, building the cardio-oncology community, detecting and treating cardiovascular events associated with immunotherapy, understanding tyrosine kinase inhibitor cardiotoxicity, and enhancing survivorship care are all priorities for the field. The path forward requires a commitment to research, education, and excellence in clinical care to improve our patients' lives.
心脏肿瘤学学科发展迅速。2019年10月3日至4日在巴西圣保罗举行的全球心脏肿瘤学峰会上,介绍了心脏肿瘤学临床医生面临的最新进展和挑战。在此,我们列出了会议讨论的本领域十大优先事项,并详细阐述应对这些挑战的潜在前进道路。确定心脏毒性的可靠预测指标、阐明心脏保护的作用、管理和预防血栓栓塞、改善造血干细胞移植结果、使心脏干预个性化、建立心脏肿瘤学领域、检测和治疗与免疫治疗相关的心血管事件、了解酪氨酸激酶抑制剂的心脏毒性以及加强生存护理,都是该领域的优先事项。前进的道路需要致力于研究、教育以及卓越的临床护理,以改善我们患者的生活。