• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

全球心脏肿瘤学峰会会议记录:心脏肿瘤学需落实的十大优先事项

Proceedings From the Global Cardio-Oncology Summit: The Top 10 Priorities to Actualize for CardioOncology.

作者信息

Lenihan Daniel J, Fradley Michael G, Dent Susan, Brezden-Masley Christine, Carver Joseph, Filho Roberto Kalil, Neilan Tomas G, Blaes Anne, Melloni Chiara, Herrmann Joerg, Armenian Saro, Thavendiranathan Paaladinesh, Armstrong Gregory T, Ky Bonnie, Hajjar Ludhmila

机构信息

Cardio-Oncology Center of Excellence, Cardiovascular Division, Department of Internal Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.

Cardio-Oncology Program, Moffitt Cancer Center, University of South Florida, Tampa, Florida, USA.

出版信息

JACC CardioOncol. 2019 Dec 17;1(2):256-272. doi: 10.1016/j.jaccao.2019.11.007. eCollection 2019 Dec.

DOI:10.1016/j.jaccao.2019.11.007
PMID:34396188
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8352295/
Abstract

The discipline of cardio-oncology has expanded at a remarkable pace. Recent developments and challenges to clinicians who practice cardio-oncology were presented at the Global Cardio-Oncology Summit on October 3 to 4, 2019, in São Paulo, Brazil. Here, we present the top 10 priorities for our field that were discussed at the meeting, and also detail a potential path forward to address these challenges. Defining robust predictors of cardiotoxicity, clarifying the role of cardioprotection, managing and preventing thromboembolism, improving hematopoietic stem cell transplant outcomes, personalizing cardiac interventions, building the cardio-oncology community, detecting and treating cardiovascular events associated with immunotherapy, understanding tyrosine kinase inhibitor cardiotoxicity, and enhancing survivorship care are all priorities for the field. The path forward requires a commitment to research, education, and excellence in clinical care to improve our patients' lives.

摘要

心脏肿瘤学学科发展迅速。2019年10月3日至4日在巴西圣保罗举行的全球心脏肿瘤学峰会上,介绍了心脏肿瘤学临床医生面临的最新进展和挑战。在此,我们列出了会议讨论的本领域十大优先事项,并详细阐述应对这些挑战的潜在前进道路。确定心脏毒性的可靠预测指标、阐明心脏保护的作用、管理和预防血栓栓塞、改善造血干细胞移植结果、使心脏干预个性化、建立心脏肿瘤学领域、检测和治疗与免疫治疗相关的心血管事件、了解酪氨酸激酶抑制剂的心脏毒性以及加强生存护理,都是该领域的优先事项。前进的道路需要致力于研究、教育以及卓越的临床护理,以改善我们患者的生活。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/8ec4fd9118d5/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/0e73dc7fcb05/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/678adadffc0a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/0a83d6cc4234/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/0e73dc7fcb05/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/4ff05de8cc29/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/8ec4fd9118d5/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/0e73dc7fcb05/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/678adadffc0a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/0a83d6cc4234/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/0e73dc7fcb05/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/4ff05de8cc29/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ca/8352295/8ec4fd9118d5/gr4.jpg

相似文献

1
Proceedings From the Global Cardio-Oncology Summit: The Top 10 Priorities to Actualize for CardioOncology.全球心脏肿瘤学峰会会议记录:心脏肿瘤学需落实的十大优先事项
JACC CardioOncol. 2019 Dec 17;1(2):256-272. doi: 10.1016/j.jaccao.2019.11.007. eCollection 2019 Dec.
2
Priorities in Cardio-Oncology Basic and Translational Science: GCOS 2023 Symposium Proceedings: State-of-the-Art Review.心脏肿瘤学基础与转化科学的优先事项:GCOS 2023研讨会论文集:最新综述
JACC CardioOncol. 2023 Sep 27;5(6):715-731. doi: 10.1016/j.jaccao.2023.08.003. eCollection 2023 Dec.
3
Permissive Cardiotoxicity: The Clinical Crucible of Cardio-Oncology.姑息性心脏毒性:心脏肿瘤学的临床严峻考验
JACC CardioOncol. 2022 Sep 20;4(3):302-312. doi: 10.1016/j.jaccao.2022.07.005. eCollection 2022 Sep.
4
Role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the European Society of Cardiology (ESC).心血管影像学在接受心脏毒性治疗的癌症患者中的作用:代表心力衰竭协会(HFA)、欧洲心血管影像协会(EACVI)和欧洲心脏病学会心脏肿瘤学委员会(ESC)的立场声明。
Eur J Heart Fail. 2020 Sep;22(9):1504-1524. doi: 10.1002/ejhf.1957. Epub 2020 Aug 21.
5
Global longitudinal strain at 3 months after therapy can predict late cardiotoxicity in breast cancer.治疗后 3 个月的整体纵向应变可预测乳腺癌的迟发性心脏毒性。
Cancer Med. 2023 Jun;12(12):13374-13387. doi: 10.1002/cam4.6039. Epub 2023 May 15.
6
Atherosclerosis With Immune Checkpoint Inhibitor Therapy: Evidence, Diagnosis, and Management: State-of-the-Art Review.免疫检查点抑制剂治疗相关动脉粥样硬化:证据、诊断与管理:最新综述
JACC CardioOncol. 2022 Dec 20;4(5):598-615. doi: 10.1016/j.jaccao.2022.11.011. eCollection 2022 Dec.
7
Immune Checkpoint Inhibitor Therapy in Oncology: Current Uses and Future Directions: State-of-the-Art Review.肿瘤学中的免疫检查点抑制剂疗法:当前应用与未来方向:最新综述
JACC CardioOncol. 2022 Dec 20;4(5):579-597. doi: 10.1016/j.jaccao.2022.09.004. eCollection 2022 Dec.
8
Cardiovascular Disease After Hematopoietic Stem Cell Transplantation in Adults: State-of-the-Art Review.成人造血干细胞移植后的心血管疾病:最新综述
JACC CardioOncol. 2024 Aug 20;6(4):475-495. doi: 10.1016/j.jaccao.2024.06.004. eCollection 2024 Aug.
9
Cardiac Magnetic Resonance in Cardio-Oncology: Advantages, Importance of Expediency, and Considerations to Navigate Pre-Authorization.心脏肿瘤学中的心脏磁共振成像:优势、时效性的重要性以及医保预授权相关考量
JACC CardioOncol. 2021 Jun 15;3(2):191-200. doi: 10.1016/j.jaccao.2021.04.011. eCollection 2021 Jun.
10
What Does a Cardio-oncology Service Offer to the Oncologist and the Haematologist?心血管肿瘤学服务为肿瘤学家和血液学家提供了什么?
Clin Oncol (R Coll Radiol). 2021 Aug;33(8):483-493. doi: 10.1016/j.clon.2021.03.012. Epub 2021 Apr 5.

引用本文的文献

1
Exosomal transfer of pro-pyroptotic miR-216a-5p exacerbates anthracycline cardiotoxicity through breast cancer-heart pathological crosstalk.促焦亡性miR-216a-5p的外泌体转移通过乳腺癌-心脏病理串扰加剧蒽环类药物心脏毒性。
Signal Transduct Target Ther. 2025 May 14;10(1):157. doi: 10.1038/s41392-025-02245-4.
2
Cardio-oncology rehabilitation and exercise: evidence, priorities, and research standards from the ICOS-CORE working group.心脏肿瘤康复与运动:ICOS-CORE工作组的证据、优先事项和研究标准
Eur Heart J. 2025 Feb 28. doi: 10.1093/eurheartj/ehaf100.
3
Discovery of plasma proteins and metabolites associated with left ventricular cardiac dysfunction in pan-cancer patients.

本文引用的文献

1
Poised to Serve a Maturing, Collaborative Field.随时准备服务于一个成熟的协作领域。
JACC CardioOncol. 2019 Jun 15;1(1):131-132. doi: 10.1016/j.jaccao.2019.06.001. eCollection 2019 Sep.
2
Efficacy of Neurohormonal Therapies in Preventing Cardiotoxicity in Patients with Cancer Undergoing Chemotherapy.神经激素疗法在预防接受化疗的癌症患者心脏毒性方面的疗效。
JACC CardioOncol. 2019 Sep;1(1):54-65. doi: 10.1016/j.jaccao.2019.08.006. Epub 2019 Sep 24.
3
Cardiovascular Toxicities Associated With Ibrutinib.伊布替尼相关心血管毒性。
泛癌患者中与左心室心脏功能障碍相关的血浆蛋白和代谢物的发现。
Cardiooncology. 2025 Feb 13;11(1):17. doi: 10.1186/s40959-025-00309-6.
4
Cancer and Heart Failure: Dangerous Liaisons.癌症与心力衰竭:危险关联
J Cardiovasc Dev Dis. 2024 Aug 27;11(9):263. doi: 10.3390/jcdd11090263.
5
Pediatric Cardio-Oncology: Screening, Risk Stratification, and Prevention of Cardiotoxicity Associated with Anthracyclines.儿科心脏肿瘤学:蒽环类药物相关心脏毒性的筛查、风险分层与预防
Children (Basel). 2024 Jul 22;11(7):884. doi: 10.3390/children11070884.
6
Understanding the biological mechanisms of cancer treatment-induced cardiac toxicity.了解癌症治疗引起心脏毒性的生物学机制。
Am Heart J Plus. 2022 Jul 13;18:100177. doi: 10.1016/j.ahjo.2022.100177. eCollection 2022 Jun.
7
Cardio-oncology: Shared Genetic, Metabolic, and Pharmacologic Mechanism.心脏肿瘤学:共同的遗传、代谢和药理学机制。
Curr Cardiol Rep. 2023 Aug;25(8):863-878. doi: 10.1007/s11886-023-01906-6. Epub 2023 Jul 26.
8
Sacubitril/valsartan for cardioprotection in breast cancer (MAINSTREAM): design and rationale of the randomized trial.沙库巴曲缬沙坦用于乳腺癌的心脏保护(MAINSTREAM):随机试验的设计和原理。
ESC Heart Fail. 2023 Oct;10(5):3174-3183. doi: 10.1002/ehf2.14466. Epub 2023 Jul 14.
9
Direct-Acting Oral Anticoagulant Therapy in Cancer Patients-A Review.癌症患者的直接口服抗凝剂治疗——综述
Cancers (Basel). 2023 May 10;15(10):2697. doi: 10.3390/cancers15102697.
10
Risk and Management of Patients with Cancer and Heart Disease.癌症与心脏病患者的风险及管理
Cardiol Ther. 2023 Jun;12(2):227-241. doi: 10.1007/s40119-023-00305-w. Epub 2023 Feb 9.
J Am Coll Cardiol. 2019 Oct 1;74(13):1667-1678. doi: 10.1016/j.jacc.2019.07.056.
4
Case 30-2019: A 65-Year-Old Woman with Lung Cancer and Chest Pain.病例30 - 2019:一名65岁患有肺癌和胸痛的女性。
N Engl J Med. 2019 Sep 26;381(13):1268-1277. doi: 10.1056/NEJMcpc1900423.
5
Medium and long-term risks of specific cardiovascular diseases in survivors of 20 adult cancers: a population-based cohort study using multiple linked UK electronic health records databases.20 种成人癌症幸存者特定心血管疾病的中远期风险:一项基于人群的队列研究,使用多个英国电子健康记录数据库进行关联
Lancet. 2019 Sep 21;394(10203):1041-1054. doi: 10.1016/S0140-6736(19)31674-5. Epub 2019 Aug 20.
6
Assessment of Prognostic Value of Left Ventricular Global Longitudinal Strain for Early Prediction of Chemotherapy-Induced Cardiotoxicity: A Systematic Review and Meta-analysis.左心室整体纵向应变评估对化疗诱导性心脏毒性早期预测的预后价值:系统评价和荟萃分析。
JAMA Cardiol. 2019 Oct 1;4(10):1007-1018. doi: 10.1001/jamacardio.2019.2952.
7
Percutaneous coronary intervention and in-hospital outcomes in patients with leukemia: a nationwide analysis.经皮冠状动脉介入治疗与白血病患者的院内转归:一项全国性分析。
Catheter Cardiovasc Interv. 2020 Jul;96(1):53-63. doi: 10.1002/ccd.28432. Epub 2019 Aug 13.
8
Percutaneous Coronary Intervention and Outcomes in Patients With Lymphoma in the United States (Nationwide Inpatient Sample [NIS] Analysis).美国淋巴瘤患者行经皮冠状动脉介入治疗和结局(全国住院患者样本[NIS]分析)。
Am J Cardiol. 2019 Oct 15;124(8):1190-1197. doi: 10.1016/j.amjcard.2019.07.015. Epub 2019 Jul 24.
9
Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Clinical Practice Guideline Update.静脉血栓栓塞症预防和治疗癌症患者:ASCO 临床实践指南更新。
J Clin Oncol. 2020 Feb 10;38(5):496-520. doi: 10.1200/JCO.19.01461. Epub 2019 Aug 5.
10
Development and validation of a multivariable prediction model for major adverse cardiovascular events after early stage breast cancer: a population-based cohort study.早期乳腺癌后主要不良心血管事件的多变量预测模型的开发和验证:基于人群的队列研究。
Eur Heart J. 2019 Dec 21;40(48):3913-3920. doi: 10.1093/eurheartj/ehz460.