University of Miami Miller School of Medicine, Miami, FL, USA.
Department of Urology, University of Miami Miller School of Medicine, Miami, FL, USA.
Andrologia. 2021 Dec;53(11):e14219. doi: 10.1111/and.14219. Epub 2021 Aug 16.
Coronavirus disease 2019 (COVID-19) is an emerging infectious disease caused by a novel coronavirus (SARS-CoV-2), which demonstrates the ability to invade endothelial cells and cause systemic inflammation. Many possible long-term sequelae of COVID-19 remain unidentified. We describe a case of a man who developed Peyronie's disease after a resolved COVID-19 infection. Erectile dysfunction was confirmed by the International Index of Erectile Function-15(IIEF) and Sexual Health Inventory for Men(SHIM) scores. A diagnosis was Peyronie's disease was confirmed on ultrasound. Furthermore, he was found to have low endothelial progenitor cells colony-forming units and low brachial artery flow-mediated vasodilation, both of that are indicative of endothelial dysfunction. This case suggests Peyronie's disease should be considered as a possible sequela of COVID-19 infection and providers should inquire about a history of COVID-19 infection in patients presenting with Peyronie's disease.
新型冠状病毒病(COVID-19)是一种由新型冠状病毒(SARS-CoV-2)引起的新发传染病,具有侵袭血管内皮细胞并引起全身炎症的能力。COVID-19 的许多可能的长期后遗症仍未被确定。我们描述了一例 COVID-19 感染后发生 Peyronie 病的男性患者。勃起功能障碍通过国际勃起功能指数-15(IIEF)和男性性功能健康问卷(SHIM)评分得到证实。超声检查确诊为 Peyronie 病。此外,他还被发现内皮祖细胞集落形成单位低,肱动脉血流介导的血管舒张功能低,这都表明存在血管内皮功能障碍。该病例提示 Peyronie 病应被视为 COVID-19 感染的一种可能后遗症,临床医生在遇到 Peyronie 病患者时应询问 COVID-19 感染史。