Connelly Zachary M, Whitaker Dustin, Dullea Alexandra, Ramasamy Ranjith
Department of Surgery, Louisiana State University Health Shreveport Shreveport, LA, USA.
Department of Urology, University of Tennessee Knoxville Knoxville, TN, USA.
Am J Clin Exp Urol. 2022 Aug 15;10(4):199-209. eCollection 2022.
SARS-CoV-2 infection arose in 2019 and has changed life as we know it. With our ever-advancing knowledge, therapies, and vaccines, more functions of the SARS-CoV-2 virus are being investigated outside of its pulmonary invasion. Here, we set out to review the current and pertinent literature on the impact of SARS-CoV-2 on the male genitourinary system including the bladder, lower urinary tract, prostate, testis, and penis. The biggest newsworthy stake was if SARS-CoV-2 could be transmitted through semen. Although initially thought to occur, more recent studies have opposed this hypothesis. Outside of the reproductive spread of SARS-CoV-2, multiple studies in this review highlight where the virus resides and what effect it may be having on this genitourinary system including increased voiding problems, viral persistence months after systemic clearance, and rare penile complications post-infection. Long-term outcomes are still needed to fully understand how SARS-CoV-2 infection can alter the genitourinary system.
严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染于2019年出现,改变了我们所熟知的生活。随着我们的知识、治疗方法和疫苗不断进步,人们正在研究SARS-CoV-2病毒在肺部侵袭之外的更多功能。在此,我们着手回顾当前关于SARS-CoV-2对男性生殖泌尿系统(包括膀胱、下尿路、前列腺、睾丸和阴茎)影响的相关文献。最具新闻价值的要点是SARS-CoV-2是否可通过精液传播。尽管最初认为会发生这种情况,但最近的研究反对这一假设。在SARS-CoV-2的生殖传播之外,本综述中的多项研究强调了病毒的存在位置以及它可能对该生殖泌尿系统产生的影响,包括排尿问题增加、全身清除数月后病毒持续存在以及感染后罕见的阴茎并发症。仍需要长期结果来全面了解SARS-CoV-2感染如何改变生殖泌尿系统。