The First Clinical Medical College of Lanzhou University, Lanzhou University, Lanzhou, China.
Department of Cardiovascular Surgery, First Hospital of Lanzhou University, Lanzhou, China.
Medicine (Baltimore). 2021 Jul 23;100(29):e26696. doi: 10.1097/MD.0000000000026696.
The prognosis of patients with aortic stenosis, in conjunction with chronic kidney disease (CKD), after transcatheter aortic valve replacement (TAVR) remains unclear. This study assessed the impact of CKD, and different stages of CKD, on prognosis of patients undergoing TAVR.
The protocol was written following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols statement guidelines. As of June 2021, we performed a comprehensive literature search on studies related to CKD and TAVR, using databases such as PubMed, Embase, Cochrane Library, and Web of Science. Two researchers independently screened the literature, extracted the data, and evaluated the risk of bias in the included studies. Then, Stata 15.0 software was used for meta-analysis.
The purpose of this study was to evaluate the effect of CKD and different stages of CKD on the prognosis of patients with TAVR. It is hoped to provide a comprehensive reference for clinical practice and related clinical trials in the future.
经导管主动脉瓣置换术（TAVR）后合并慢性肾脏病（CKD）的主动脉瓣狭窄患者的预后仍不清楚。本研究评估了 CKD 及其不同分期对 TAVR 患者预后的影响。
该方案是按照系统评价和荟萃分析报告规范的首选报告项目声明指南编写的。截至 2021 年 6 月，我们使用 PubMed、Embase、Cochrane 图书馆和 Web of Science 等数据库对与 CKD 和 TAVR 相关的研究进行了全面的文献检索。两名研究人员独立筛选文献、提取数据，并评估纳入研究的偏倚风险。然后，使用 Stata 15.0 软件进行荟萃分析。
本研究旨在评估 CKD 及其不同分期对 TAVR 患者预后的影响。希望为未来的临床实践和相关临床试验提供全面的参考。
