Department of General Surgery, Jiangning Hospital, Nanjing, Jiangsu, China.
Department of General Surgery, Jinling Hospital, Nanjing, Jiangsu, China.
Langenbecks Arch Surg. 2021 Dec;406(8):2837-2848. doi: 10.1007/s00423-021-02301-x. Epub 2021 Aug 16.
The purpose of this study is to investigate the effects of different preoperative enteral nutrition feeding routes on the duration of gastrointestinal decompression after definitive surgery for small intestinal fistula.
From January 2015 to June 2019, patients with small intestinal fistula and receiving a definitive surgery were enrolled. According to the feeding route, patients were divided into a nasointestinal tube group and a nasogastric tube group. Clinical characteristics of the two groups were analyzed, and the influence of the two route on the recovery of gastrointestinal function was evaluated.
A total of 151 patients were enrolled in our study. There were 49 patients in the nasogastric tube group, and 102 patients in the nasointestinal tube group. Enteral nutrition via nasogastric feeding route had a positive effect on shortening the duration of gastrointestinal decompression (adjusted HR = 2.488, 95% CI: 1.692-3.659, P < 0.001). After propensity matching (PM), 44 patients were enrolled (22 vs 22). EN via nasogastric tube was a positive factor for getting rid of gastrointestinal decompression (adjusted HR = 3.563, 95% CI: 1.639-7.746, P = 0.001).
Preoperative enteral nutrition via nasogastric route can reduce the duration of gastrointestinal decompression after definitive surgery for small intestinal fistula.
本研究旨在探讨不同术前肠内营养喂养途径对小肠瘘确定性手术后胃肠减压时间的影响。
2015 年 1 月至 2019 年 6 月，纳入小肠瘘并接受确定性手术的患者。根据喂养途径将患者分为鼻肠管组和鼻胃管组。分析两组患者的临床特征，评估两种途径对胃肠功能恢复的影响。
本研究共纳入 151 例患者。鼻胃管组 49 例，鼻肠管组 102 例。经鼻胃管肠内营养对缩短胃肠减压时间有积极作用（调整 HR=2.488，95%CI：1.692-3.659，P<0.001）。在倾向评分匹配（PM）后，共纳入 44 例患者（22 例 vs 22 例）。经鼻胃管肠内营养是摆脱胃肠减压的一个积极因素（调整 HR=3.563，95%CI：1.639-7.746，P=0.001）。
术前经鼻胃管肠内营养可减少小肠瘘确定性手术后胃肠减压时间。
