Iaroshinskiĭ Iu N, Shraĭber A A, Ostraovskaia E A, Bogonatov B N, Fursov B A
Arkh Patol. 1987;49(11):44-9.
Four varieties of infectious endocarditis were identified after cardiac valve bioprostheses: early acute, early subacute, late acute, and late subacute forms. Any of these forms may be of bacterial, fungal, or mixed (bacterial and fungal) origin. In the early forms, the infection was of exogenous origin, with a predominance of Gram-positive organisms, whereas in the late forms it was endogenous with a preponderance of Gram-negative flora. The hallmarks of fungal thromboendocarditis were an early massive thrombosis of the bioprosthesis, multiple thromboembolism, and an absence of cellular reaction in the cuspal tissue. In the subacute bacterial endocarditis, progressive dysfunction of the bioprosthesis resulting from calcination of bacteria-containing cusps and thrombi was noted.
早期急性、早期亚急性、晚期急性和晚期亚急性形式。这些形式中的任何一种都可能是细菌、真菌或混合（细菌和真菌）起源。在早期形式中，感染是外源性的，以革兰氏阳性菌为主，而在晚期形式中是内源性的，革兰氏阴性菌占优势。真菌性血栓性心内膜炎的特征是生物假体早期大量血栓形成、多发性血栓栓塞以及瓣叶组织中无细胞反应。在亚急性细菌性心内膜炎中，注意到含细菌的瓣叶和血栓钙化导致生物假体进行性功能障碍。
