Savin R C
Cutis. 1978 Mar;21(3):403-7.
A new potent topical corticosteroid, desoximetasone, was clinically evaluated in several hundred patients with steroid-responsive dermatoses. Both short-term and long-term comparative studies showed desoximetasone emollient cream (0.25 percent) to be highly effective. Studies comparing betamethasone valerate cream C0. p1 percent) with desoximetasone emollient cream (0.25 percent) showed the new topical steroid to be clinically superior in the relief of moderate and severe inflammatory manifestations of psoriasis and atopic dermatitis. In addition, desoximetasone was found to be safe, well tolerated, and accepted by the patients.
一种新型强效外用皮质类固醇——去氧米松,在数百名对类固醇有反应的皮肤病患者身上进行了临床评估。短期和长期的对比研究均表明,去氧米松润肤霜(0.25%)具有高效性。将戊酸倍他米松乳膏(0.1%)与去氧米松润肤霜(0.25%)进行比较的研究显示,这种新型外用类固醇在缓解银屑病和特应性皮炎的中度及重度炎症表现方面在临床上更具优势。此外,发现去氧米松安全、耐受性良好且为患者所接受。