Morley D, Chang T M
Artifical Cells and Organs Research Centre Faculty of Medicine, McGill University, Montreal, P.Q., Canada.
Biomater Artif Cells Artif Organs. 1987;15(3):617-32. doi: 10.3109/10731198709117559.
Different thicknesses of a cellulose nitrate (CN) coating were applied to petroleum pitch bead activated charcoal. The effect of this on the adsorption of small and middle molecules in vitro was studied. This was done by measuring the rate of adsorption of Vitamin B12, creatinine and uric acid from aqueous solution by activated charcoal having CN coatings of varying thickness (0.1% to 4.0% by weight). A CN coating weight of up to 0.2% caused negligible or no decrease in the rate of adsorption of all three solutes as compared with uncoated charcoal. Coating weights greater than 0.2% caused a significant decrease in the rate of adsorption of Vitamin B12, and uric acid but had little effect on the rate of adsorption of creatinine. Coating weights greater than 1.8% caused a significant decrease in the rate of adsorption of creatinine.
将不同厚度的硝酸纤维素（CN）涂层涂覆在石油沥青珠状活性炭上。研究了其对体外中小分子吸附的影响。通过测量不同厚度（0.1%至4.0%重量）CN涂层的活性炭从水溶液中吸附维生素B12、肌酐和尿酸的速率来进行此项研究。与未涂覆的活性炭相比，CN涂层重量高达0.2%时，所有三种溶质的吸附速率降低可忽略不计或没有降低。涂层重量大于0.2%时，维生素B12和尿酸的吸附速率显著降低，但对肌酐的吸附速率影响不大。涂层重量大于1.8%时，肌酐的吸附速率显著降低。
