产前磁共振成像显示孤立性完全透明隔缺如胎儿的学龄期结局
School-Age Outcome of Fetuses with Isolated Complete Septum Pellucidum Agenesis at Prenatal Magnetic Resonance Imaging.
作者信息
Righini Andrea, Izzo Giana, Doneda Chiara, Scelsa Barbara, Parazzini Cecilia
机构信息
Pediatric Radiology and Neuroradiology Department, Children's Hospital V. Buzzi, Milan, Italy.
Pediatric Neurology Department, Children's Hospital V. Buzzi, Milan, Italy.
出版信息
Neuropediatrics. 2022 Feb;53(1):26-31. doi: 10.1055/s-0041-1733985. Epub 2021 Aug 17.
OBJECTIVE
To the best of our knowledge, there have not been studies to address the issue of long-term follow-up of patients with prenatal diagnosis of isolated complete septum pellucidum agenesis (SPA). The aim of this study was to acquire information about the school-age outcome of such patients as a resource for counseling parents receiving this prenatal finding.
METHODS
From a large fetal magnetic resonance (MR) database, we selected only those cases with isolated complete SPA as confirmed by two senior pediatric neuroradiologists in consensus; we then gathered information from the parents of those children who had reached the school age.
RESULTS
None among the 12 cases (mean age at follow-up: 8.7 years, range: 6-13 year) of the resulting final cohort presented visual or stature deficits; only one required special teaching assistance in school. All other 11 children resulted without any notable academic issue.
CONCLUSION
Our report may provide information of practical value about the school-age outcome of fetuses detected by prenatal MR imaging to carry isolated complete SPA.
目的
就我们所知，尚未有研究探讨产前诊断为单纯性透明隔缺如（SPA）的患者的长期随访问题。本研究的目的是获取此类患者学龄期结局的信息，为接受这一产前检查结果的家长提供咨询参考。
方法
从一个大型胎儿磁共振（MR）数据库中，我们仅选择了经两位资深儿科神经放射科医生一致确认的单纯性完全性SPA病例；然后我们收集了那些已达到学龄期儿童家长的信息。
结果
最终队列中的12例病例（随访时平均年龄：8.7岁，范围：6 - 13岁）均未出现视力或身高缺陷；只有1例在学校需要特殊教学帮助。其他11名儿童均未出现任何显著的学业问题。
结论
我们的报告可能为产前MR成像检测出单纯性完全性SPA的胎儿的学龄期结局提供具有实际价值的信息。
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