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一名无已知肾上腺功能不全的成年人因流感和破伤风疫苗接种继发肾上腺危象:自身免疫性肾上腺炎病例

Adrenal Crisis Secondary to Influenza and Tetanus Vaccination in an Adult Without Known Adrenal Insufficiency: A Case of Autoimmune Adrenalitis.

作者信息

Kamath Shiwani, Khabra Jessica K, Desai Parth, Frunzi Johnathan

机构信息

Internal Medicine, Medical Center of Trinity, Trinity, USA.

Critical Care Medicine, Medical Center of Trinity, Trinity, USA.

出版信息

Cureus. 2021 Jul 11;13(7):e16312. doi: 10.7759/cureus.16312. eCollection 2021 Jul.

Abstract

Adrenal crisis (AC) is a rare but known life-threatening condition in patients with adrenal insufficiency (AI). We report the case of a 21-year-old without known AI who developed AC after routine vaccinations. Workup revealed that the patient had underlying, undiagnosed autoimmune adrenalitis. This is the first report of AC induced by influenza and diphtheria, tetanus, and acellular pertussis (DTaP) vaccinations in a patient without known AI.

摘要

肾上腺危象(AC)在肾上腺功能不全(AI)患者中是一种罕见但已知的危及生命的病症。我们报告了一例21岁、无已知AI病史的患者,其在常规接种疫苗后发生了AC。检查发现该患者患有潜在的、未被诊断出的自身免疫性肾上腺炎。这是首例关于在无已知AI的患者中,流感疫苗以及白喉、破伤风和无细胞百日咳(DTaP)疫苗诱发AC的报告。

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