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1例新冠病毒感染缓解后发生急性白血病的病例;探寻可能关联的迫切需求

A Case of Acute Leukemia Following Remission of COVID-19 Infection; an Urge to Search for a Probable Association.

作者信息

Nekooghadam Seyyed Mojtaba, Moradi Afshin, Karimi Toudeshki Kimia, Pishgahi Mehdi

机构信息

Internal Department, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Pathology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Arch Acad Emerg Med. 2021 Jul 24;9(1):e51. eCollection 2021.

Abstract

Many aspects of Covid-19 infection, especially its complications and long-term health consequences are still unknown. Several reports concerning concomitant covid-19 infection and hematological disorders have been published recently. We aim to present a unique case of acute myeloid leukemia in a 61-year-old man with a previous history of covid-19 infection 40 days ago, with near complete resolution of signs and symptoms attributable to covid-19 infection. After 3 weeks, the patient presented again with progressive weakness, nausea, vomiting, and epigastric pain. No evidence of active covid-19 infection was observed. Instead, remarkable drop of hemoglobin and platelets relative to the values recorded in the discharge notes of the patient was observed. Further workup of the patient revealed evidence of acute leukemia and severe bone marrow involvement. We decided to present the current case as a concerning probable association.

摘要

新冠病毒感染的许多方面,尤其是其并发症和长期健康后果仍不明确。最近已发表了几篇关于新冠病毒合并感染与血液系统疾病的报告。我们旨在介绍一例独特病例,一名61岁男性,40天前有新冠病毒感染史,当时新冠病毒感染的体征和症状几乎完全消退。3周后,患者再次出现进行性虚弱、恶心、呕吐和上腹部疼痛。未观察到新冠病毒活跃感染的证据。相反,观察到血红蛋白和血小板相对于患者出院记录中的值显著下降。对该患者的进一步检查发现了急性白血病和严重骨髓受累的证据。我们决定将该病例作为一种可能存在的相关情况进行介绍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e874/8366460/443d1776659c/aaem-9-e51-g001.jpg

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