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全髋关节置换术后患者报告的疼痛和阿片类药物消耗:直接前入路与后入路的比较。

Postoperative Patient-reported Pain and Opioid Consumption After Total Hip Arthroplasty: A Comparison of the Direct Anterior and Posterior Approaches.

机构信息

From the Adult Reconstruction and Joint Replacement Service, Hospital for Special Surgery (Bovonratwet, Chen, Shen, Ondeck, Kunze, and Su); Department of Orthopaedic Surgery, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY (Bovonratwet, Shen, Ondeck, and Kunze).

出版信息

J Am Acad Orthop Surg. 2022 Jan 1;30(1):e108-e117. doi: 10.5435/JAAOS-D-21-00082.

Abstract

INTRODUCTION

Although one of the touted benefits of the direct anterior approach (DAA) includes decreased postoperative pain, there is no consensus on the effect of surgical approach on postoperative pain and subsequent analgesic consumption.

METHODS

Consecutive patients undergoing total hip arthroplasty by a single surgeon from May 2016 to March 2020 were identified. Procedures were categorized as DAA or posterior approach. Patient demographics and surgical details were assessed. Patient-reported maximum pain by postoperative day (POD), total opioid consumption during hospitalization, and whether the patient required a refill of opioid prescription within 3 months after discharge were compared between the two surgical approaches through multivariate analyses.

RESULTS

A total of 611 patients were included in this study (447 DAA and 164 posterior approaches). On multivariate analyses that controlled for preoperative/intraoperative differences, patients in the DAA group had lower average maximum reported pain (0 to 10 scale) on POD #0 (6.5 versus 6.8, P = 0.034) and POD #1 (5.4 versus 6.1, P = 0.018). However, the DAA was not associated with a statistically significant reduction in total inpatient oral morphine equivalents consumed (79.8 versus 100.1, P = 0.486). Furthermore, there was no association between surgical approach and opioid prescription refill within 3 months after discharge (P = 0.864).

DISCUSSION

The DAA was associated with slightly lower patient-reported pain. Furthermore, statistical analysis did not provide the necessary evidence to reject the null hypothesis, which was that there would be no difference in opioid utilization between the two approaches. Other perioperative factors may be more important to opioid use reduction than the surgical approach alone.

摘要

简介

虽然直接前方入路(DAA)的一个被吹捧的好处包括术后疼痛减轻,但手术入路对术后疼痛和随后的镇痛消耗的影响尚无共识。

方法

确定了 2016 年 5 月至 2020 年 3 月期间由一位外科医生进行的全髋关节置换术的连续患者。手术分为 DAA 或后入路。评估了患者人口统计学和手术细节。通过多元分析比较了两种手术方法在术后第 0 天(POD)患者报告的最大疼痛、住院期间总阿片类药物消耗以及患者在出院后 3 个月内是否需要阿片类药物处方续药之间的差异。

结果

本研究共纳入 611 例患者(DAA 组 447 例,后入路组 164 例)。在控制术前/术中差异的多元分析中,DAA 组患者在 POD #0(6.5 与 6.8,P = 0.034)和 POD #1(5.4 与 6.1,P = 0.018)时的平均最大报告疼痛较低。然而,DAA 与住院期间口服吗啡等效物消耗总量(79.8 与 100.1,P = 0.486)无统计学显著降低相关。此外,两种手术方法与出院后 3 个月内阿片类药物处方续药之间无关联(P = 0.864)。

讨论

DAA 与患者报告的疼痛稍低有关。此外,统计分析并未提供必要的证据来拒绝无效假设,即两种方法之间在阿片类药物使用方面没有差异。其他围手术期因素可能比手术方法本身更重要,有助于减少阿片类药物的使用。

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