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手术入路并不影响全髋关节置换术后慢性阿片类药物的使用。

Surgical Approach Does Not Affect Chronic Opioid Usage After Total Hip Arthroplasty.

机构信息

Department of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

Department of Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas; Arkansas Department of Health, Little Rock, Arkansas.

出版信息

J Arthroplasty. 2023 Sep;38(9):1812-1816. doi: 10.1016/j.arth.2023.03.085. Epub 2023 Apr 3.

Abstract

BACKGROUND

Three different surgical approaches (the direct anterior, antero-lateral, and posterior) are commonly used for total hip arthroplasty (THA). Due to an internervous and intermuscular approach, the direct anterior approach may result in less postoperative pain and opioid use, although all 3 approaches have similar outcomes 5 years after surgery. Perioperative opioid medication consumption poses a dose-dependent risk of long-term opioid use. We hypothesized that the direct anterior approach is associated with less opioid usage over 180 days after surgery than the antero-lateral or posterior approaches.

METHODS

A retrospective cohort study was performed including 508 patients (192 direct anterior, 207 antero-lateral, and 109 posterior approaches). Patient demographics and surgical characteristics were identified from the medical records. The state prescription database was used to determine opioid use 90 days before and 1 year after THA. Regression analyses controlling for sex, race, age, and body mass index were used to determine the effect of surgical approach on opioid use over 180 days after surgery.

RESULTS

No difference was seen in the proportion of long-term opioid users based on approach (P = .78). There was no significant difference in the distribution of opioid prescriptions filled between surgical approach groups in the year after surgery (P = .35). Not taking opioids 90 days prior to surgery, regardless of approach, was associated with a 78% decrease in the odds of becoming a chronic opioid user (P < .0001).

CONCLUSION

Opioid use prior to surgery, rather than THA surgical approach, was associated with chronic opioid consumption following THA.

摘要

背景

全髋关节置换术(THA)常采用三种不同的手术入路(直接前入路、前外侧入路和后外侧入路)。由于神经间和肌肉间的入路,直接前入路可能导致术后疼痛和阿片类药物使用减少,尽管三种入路在术后 5 年均有相似的结果。围手术期阿片类药物的使用与长期使用阿片类药物存在剂量依赖性风险。我们假设与前外侧或后外侧入路相比,直接前入路在术后 180 天内的阿片类药物使用量较少。

方法

本回顾性队列研究纳入了 508 例患者(192 例直接前入路、207 例前外侧入路和 109 例后外侧入路)。从病历中确定患者的人口统计学和手术特征。使用州处方数据库确定 THA 术前 90 天和术后 1 年的阿片类药物使用情况。采用控制性别、种族、年龄和体重指数的回归分析来确定手术入路对术后 180 天内阿片类药物使用的影响。

结果

不同入路的长期阿片类药物使用者比例无差异(P=0.78)。术后一年,各组之间阿片类药物处方的分布无显著差异(P=0.35)。无论手术入路如何,在手术前 90 天不使用阿片类药物与成为慢性阿片类药物使用者的几率降低 78%相关(P<0.0001)。

结论

术前阿片类药物的使用,而不是 THA 的手术入路,与 THA 后慢性阿片类药物的使用相关。

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