Gambardella P, Sticchi R, Ferrante P, D'Aponte D
Institute of Human Physiological Sciences, University of Naples.
Int J Vitam Nutr Res. 1987;57(4):441-5.
Authors have studied the effects of purified hyper- and hypoproteic diets on fetal and postnatal (not further than 40th day) stage of the rat, when cell subdivision process is faster in all the organs. Litters were grouped according to mother's and rats' (after lactation) diet. Growth of rats, brain DNA and hystology of organs were evaluated. Results of the study have shown that both diets cause alterations on growth and brain DNA and also morphological changes of several organs. Yet, it looks like major effects are produced by hypoproteic diet since it causes, apart from general damage, an irreversible delay in growing process which is not reset by normal feeding.
作者研究了高蛋白质和低蛋白质纯化饮食对大鼠胎儿期及出生后（不超过第40天）阶段的影响，此阶段所有器官的细胞分裂过程都更快。根据母鼠和幼鼠（哺乳期后）的饮食对幼崽进行分组。评估了大鼠的生长、脑DNA及器官组织学情况。研究结果表明，两种饮食都会对生长和脑DNA产生影响，也会导致多个器官的形态变化。然而，低蛋白质饮食似乎产生了主要影响，因为它除了造成一般性损害外，还会导致生长过程出现不可逆的延迟，即使恢复正常饮食也无法消除。
