Greco A M, Boschi V, Boschi G, de Franciscis A
Arch Sci Med (Torino). 1980 Oct-Dec;137(4):621-5.
Nests of rats, generated by mothers receiving synthetic diets of different protein content during gestation and in post-pregnancy phase, have been kept under observation during suckling and after weaning care being taken that offspring received the same diet as characterised maternal feeding. It was found that in the animals receiving hypoproteic diet (6% proteins), early induced malnutrition extended up to the 40th day of life, namely the term for the cellular subdivision of almost all organs, cuts body growth by about 80% compared to control rats, and is accompanied by a remarkable drop in packed-cell volume and haemoglobin value. In parallel, the electrophoretic pictures of hypoproteic rats were characterised by a drop in serous albumin, offset by a marked rise in beta and gamma globulin, Finally, evaluation of the weigh ratios between the brain and other organs of vital importance, underlines the preferential growth of the cerebral mass in rats receiving an inadequate protein supply.
对孕期和产后接受不同蛋白质含量合成饮食的母鼠所产幼鼠窝进行了观察，在哺乳期间以及断奶后都悉心照料幼崽，确保其食用与母鼠相同的饮食。结果发现，食用低蛋白饮食（6%蛋白质）的动物，早期诱发的营养不良会持续到生命的第40天，即几乎所有器官细胞细分的时期，与对照大鼠相比，身体生长减少约80%，同时红细胞压积和血红蛋白值显著下降。与此同时，低蛋白大鼠的电泳图谱表现为血清白蛋白下降，β和γ球蛋白显著上升。最后，对大脑与其他重要器官之间的重量比进行评估，结果显示，蛋白质供应不足的大鼠大脑质量优先增长。
