Dermatologist, Dr. Sukran Sarigul Guduk Dermatology Clinic, Istanbul, Turkey.
Department of Dermatology, School of Medicine, Haliç University, Istanbul, Turkey.
J Cosmet Laser Ther. 2021 May 19;23(3-4):52-54. doi: 10.1080/14764172.2021.1967997. Epub 2021 Aug 18.
Delayed inflammatory reactions (DIRs) associated with hyaluronic acid injections are not rare and can be seen in up to 4.25% of patients. Although the exact mechanism is not clear, several triggering factors, including infections, trauma, and dental procedures, were reported in the literature. A 43-year-old female patient treated with HA fillers developed an inflammatory reaction following vaccination in all areas of injection, including temples, lips, and lower eyelids. Systemic steroid and ciprofloxacin were used as a first-line treatment without response. Colchicine 1 mg/day along with hyaluronidase in lower eyelids improved all lesions successfully.
与透明质酸注射相关的迟发性炎症反应（DIRs）并不罕见，多达 4.25%的患者会出现这种反应。尽管确切的机制尚不清楚，但文献中报道了一些触发因素，包括感染、外伤和牙科手术。一位 43 岁的女性患者在接受 HA 填充物治疗后，在所有注射部位（包括太阳穴、嘴唇和下眼睑）接种疫苗后出现炎症反应。一线治疗使用了全身类固醇和环丙沙星，但没有效果。在下眼睑使用秋水仙碱 1mg/天和透明质酸酶成功改善了所有病变。
