短生育间隔对埃塞俄比亚新生儿、婴儿和五岁以下儿童死亡率的影响：使用逆概率治疗加权的全国代表性观察研究。

Effects of short birth interval on neonatal, infant and under-five child mortality in Ethiopia: a nationally representative observational study using inverse probability of treatment weighting.

机构信息

St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia

Centre for Women's Health Research, School of Medicine and Public Health, The University of Newcastle, Callaghan, New South Wales, Australia.

出版信息

BMJ Open. 2021 Aug 18;11(8):e047892. doi: 10.1136/bmjopen-2020-047892.

DOI:10.1136/bmjopen-2020-047892

PMID:34408041

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8375759/

Abstract

OBJECTIVE

To assess the effect of short birth interval (SBI) on neonatal, infant, and under-five mortality in Ethiopia.

DESIGN

A nationally representative cross-sectional survey.

SETTING

This study used data from the Ethiopia Demographic and Health Survey 2016.

PARTICIPANTS

A total of 8448 women who had at least two live births during the 5 years preceding the survey were included in the analysis.

OUTCOME MEASURES

Neonatal mortality (death of the child within 28 days of birth), infant mortality (death between birth and 11 months) and under-five mortality (death between birth and 59 months) were the outcome variables.

METHODS

Weighted logistic regression analysis based on inverse probability of treatment weights was used to estimate exposure effects adjusted for potential confounders.

RESULTS

The adjusted ORs (AORs) of neonatal mortality were about 85% higher among women with SBI (AOR=1.85, 95% CI=1.19 to 2.89) than those without. The odds of infant mortality were twofold higher (AOR=2.16, 95% CI=1.49 to 3.11) among women with SBI. The odds of under-five child mortality were also about two times (AOR=2.26, 95% CI=1.60 to 3.17) higher among women with SBI.

CONCLUSION

SBI has a significant effect on neonatal, infant and under-five mortality in Ethiopia. Interventions targeting SBI are warranted to reduce neonatal, infant and under-five mortality.

摘要

目的

评估短生育间隔（SBI）对埃塞俄比亚新生儿、婴儿和五岁以下儿童死亡率的影响。

设计

全国代表性的横断面调查。

地点

本研究使用了 2016 年埃塞俄比亚人口与健康调查的数据。

参与者

共有 8448 名在调查前 5 年内至少有两次活产的妇女被纳入分析。

结局指标

新生儿死亡率（出生后 28 天内儿童死亡）、婴儿死亡率（出生至 11 个月期间死亡）和五岁以下儿童死亡率（出生至 59 个月期间死亡）是结局变量。

方法

采用基于治疗逆概率加权的加权逻辑回归分析，估计调整潜在混杂因素后的暴露效应。

结果

与无 SBI 的妇女相比，SBI 妇女的新生儿死亡率调整后的比值比（AOR）约高 85%（AOR=1.85，95%CI=1.19 至 2.89）。SBI 妇女的婴儿死亡率是无 SBI 妇女的两倍（AOR=2.16，95%CI=1.49 至 3.11）。SBI 妇女的五岁以下儿童死亡率也约高出两倍（AOR=2.26，95%CI=1.60 至 3.17）。