Rompel H, Segal H
J Int Med Res. 1978;6(2):126-32. doi: 10.1177/030006057800600210.
A study designed to assess the relative efficacy of chlorpromazine and Serenace in the control of chronic schizophrenics is described. Twenty-five cases were selected for the study and were randomly allocated to treatment. The condition of the patients was assessed at fortnightly intervals over the eight-week duration of trial period. No significant differences in side-effects emerged in patients on chlorpromazine and Serenace in the dosages administered. The statistically significant trends all showed a superiority of Serenace above chlorpromazine which was in accord with the clinical picture.
本文描述了一项旨在评估氯丙嗪和舒必利对慢性精神分裂症患者控制效果的相对疗效的研究。该研究选取了25例患者，并将他们随机分配接受治疗。在为期八周的试验期内，每隔两周对患者的病情进行评估。在给予的剂量下，服用氯丙嗪和舒必利的患者在副作用方面未出现显著差异。具有统计学意义的趋势均显示舒必利优于氯丙嗪，这与临床情况相符。
