Mizumatsu Shinichiro, Ryu Hiroshi, Nomura Kei, Yoshikawa Satoshi, Inoue Norio
CyberKnife Center, Aoyama General Hospital, Toyokawa, JPN.
Cerebrospinal Center, Aoyama General Hospital, Toyokawa, JPN.
Cureus. 2021 Jul 14;13(7):e16393. doi: 10.7759/cureus.16393. eCollection 2021 Jul.
Myxofibrosarcoma (MFS) is one of the most common soft tissue sarcomas. Low-grade MFS has a high local recurrence rate, similar to that of high-grade MFS. Hence, appropriate adjuvant therapy is required to control low-grade MFS. In this report, we present a case in which recurrent low-grade MFS was successfully treated with stereotactic body radiation therapy (SBRT) using CyberKnife® (CK) (Accuray Incorporated, Sunnyvale, CA). A 76-year-old man underwent SBRT using CK for recurrent low-grade MFS in the right posterior chest wall after undergoing resection and skin grafting four and three times, respectively. We planned CK treatment separately for each in two parts. For the lesion on the scapula side, the target volume was 109 cm and the total prescribed dose was 34.6 Gy, while the lesion on the spinal side had a target volume of 72 cm and a total prescribed dose of 36 Gy, both in five fractions. Each SBRT was performed on alternate days in a span of 14 days. The tumors gradually reduced in size with tolerable levels of toxicity. SBRT using CK could be a safe and effective adjuvant therapy for low-grade MFS.
黏液纤维肉瘤（MFS）是最常见的软组织肉瘤之一。低级别MFS的局部复发率较高，与高级别MFS相似。因此，需要适当的辅助治疗来控制低级别MFS。在本报告中，我们介绍了一例复发性低级别MFS患者，通过使用射波刀（CK）（Accuray Incorporated，加利福尼亚州桑尼维尔）进行立体定向体部放射治疗（SBRT）成功治愈。一名76岁男性在分别接受了四次和三次切除及植皮手术后，因右后胸壁复发性低级别MFS接受了CK的SBRT治疗。我们分两部分分别为每个病灶制定了CK治疗计划。对于肩胛骨侧的病灶，靶体积为109 cm³，总处方剂量为34.6 Gy，而脊柱侧的病灶靶体积为72 cm³，总处方剂量为36 Gy，均分五次给予。每次SBRT在14天内隔天进行。肿瘤大小逐渐缩小，毒性水平可耐受。使用CK进行SBRT可能是治疗低级别MFS的一种安全有效的辅助治疗方法。
