一线安罗替尼联合立体定向体部放疗治疗一名老年肺肉瘤样癌患者
First-Line Anlotinib Combined with Stereotactic Body Radiation Therapy for an Octogenarian with Pulmonary Carcinosarcoma.
作者信息
Liang Long, Chen Taiyu, Ren Tao, Mao Mian, Wang Keli, Tang Chunhan, Xiao Juan, Jia Hongyuan, Chen Wenli, Wang Qifeng, Li Tao
机构信息
Department of Radiation Oncology, Sichuan Cancer Hospital and Institution, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Radiation Oncology Key Laboratory of Sichuan Province, Chengdu, People's Republic of China.
Clinical Medical College of Chengdu Medical College, Chengdu, 610500, People's Republic of China.
出版信息
Cancer Manag Res. 2022 Jan 6;14:103-106. doi: 10.2147/CMAR.S344149. eCollection 2022.
Pulmonary carcinosarcoma (PC) is a rare and highly malignant type of non-small cell lung cancer (NSCLC) that is insensitive to radiotherapy and chemotherapy and has a poor prognosis. Here, we report a case of an 88-year-old patient with inoperable PC and a history of cerebral infarction who was treated with first-line anlotinib combined with stereotactic body radiation therapy (SBRT). The therapeutic response has sustained for 10 months. Our work suggests that SBRT combined with anlotinib may be a safe and effective treatment strategy for octogenarians with PC.
肺肉瘤样癌（PC）是一种罕见且高度恶性的非小细胞肺癌（NSCLC），对放疗和化疗不敏感，预后较差。在此，我们报告一例88岁的不可切除PC患者，有脑梗死病史，接受了一线安罗替尼联合立体定向体部放疗（SBRT）治疗。治疗反应持续了10个月。我们的工作表明，SBRT联合安罗替尼可能是治疗老年PC患者的一种安全有效的治疗策略。
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