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吸附变色研究。I:吸附变色螺吡喃与一些药用固体的结合

Studies on adsorptiochromism. I: Binding of adsorptiochromic spiropyrans to some pharmaceutically useful solids.

作者信息

Connors K A, Jozwiakowski M J

机构信息

School of Pharmacy, University of Wisconsin, Madison 53706.

出版信息

J Pharm Sci. 1987 Dec;76(12):892-7. doi: 10.1002/jps.2600761210.

DOI:10.1002/jps.2600761210
PMID:3440933
Abstract

The adsorption of four adsorptiochromic spiropyrans to many solids (silica gel, silicic acid, fumed silica, alumina, microcrystalline cellulose, talc, titanium dioxide) was studied at 25 degrees C from cyclohexane solution. Nineteen adsorption isotherms were determined; and the binding data were fitted to the Langmuir equation. A model for binding of adsorptiochromic substances is described, and the parameters of the model are related to the experimental binding constant K.

摘要

在25摄氏度下,研究了四种吸附变色螺吡喃从环己烷溶液中对多种固体(硅胶、硅酸、气相二氧化硅、氧化铝、微晶纤维素、滑石、二氧化钛)的吸附。测定了19种吸附等温线;并将结合数据拟合到朗缪尔方程。描述了吸附变色物质的结合模型,且该模型的参数与实验结合常数K相关。

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