军团菌与新型冠状病毒2019（SARS-CoV-2）合并感染：一例病例报告。
Co-infection with Legionella and SARS-CoV-2: a case report.
作者信息
Shimizu Masaru, Chihara Yusuke, Satake Sakiko, Yone Astuko, Makio Mari, Kitou Hideki, Takeda Tomohiro
机构信息
Department of Anesthesia and Perioperative Care, University of California San Francisco, 505 Parnassus Ave, San Francisco, CA, 94143, USA.
Department of Pulmonary Medicine, Uji-Tokushukai Medical, 145 Ishibashi Makishimacho, Uji, Kyoto, Japan.
出版信息
JA Clin Rep. 2021 Aug 18;7(1):62. doi: 10.1186/s40981-021-00467-3.
INTRODUCTION
We report a case of COVID-19 with Legionella co-infection that was treated successfully.
CASE REPORT
A 73-year-old man presented to the hospital with symptoms of fatigue that continued for the next 5 days. The patient was receiving docetaxel and prednisolone chemotherapy for prostate cancer. Laboratory findings on admission showed positive urine Legionella antigen test and SARS-CoV-2 test. He was administered antiviral and antibacterial agents, and a corticosteroid. Pneumonia exacerbated on day 2 of hospitalization. The patient underwent tracheal intubation and began receiving multidisciplinary care. On day 8 of hospitalization, his oxygenation improved, and the patient was extubated. He discharged on day 27 of hospitalization.
CONCLUSIONS
The patient had a favorable outcome with early diagnosis and early treatment of both diseases. Patients with severe COVID-19 disease need to be evaluated for co-infection. Further, early diagnosis and early treatment of the microbial bacteria causing the co-infection are important.
引言
我们报告一例成功治疗的新型冠状病毒肺炎合并军团菌感染病例。
病例报告
一名73岁男性因疲劳症状入院，该症状持续了5天。患者正在接受多西他赛和泼尼松龙化疗以治疗前列腺癌。入院时实验室检查结果显示尿军团菌抗原检测和严重急性呼吸综合征冠状病毒2（SARS-CoV-2）检测呈阳性。给予其抗病毒、抗菌药物及一种皮质类固醇。住院第2天肺炎加重。患者接受气管插管并开始接受多学科护理。住院第8天，其氧合改善，患者拔管。患者于住院第27天出院。
结论
通过对两种疾病的早期诊断和早期治疗，患者获得了良好的预后。重症新型冠状病毒肺炎患者需要评估是否合并感染。此外，对引起合并感染的微生物细菌进行早期诊断和早期治疗很重要。
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