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卵巢交界性肿瘤的诊断线索:影像学指南。

Clues to the diagnosis of borderline ovarian tumours: An imaging guide.

机构信息

Department of Radiology, Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.

Department of Pathology, Instituto Português de Oncologia de Lisboa Francisco Gentil, NOVA Medical School, Lisbon, Portugal.

出版信息

Eur J Radiol. 2021 Oct;143:109904. doi: 10.1016/j.ejrad.2021.109904. Epub 2021 Aug 10.

Abstract

Borderline Ovarian Tumours (BOTs) are an interesting subset of epithelial neoplasms defined histologically by atypical epithelial proliferation without stromal invasion. These tumours typically affect young women in the reproductive age group and have a good prognosis. Although ultrasonography is the primary screening imaging technique in the evaluation of any suspected adnexal mass, grey-scale and colour Doppler have limited value in characterizing BOTs. Thus, a pelvic magnetic resonance imaging (MRI) is recommended for further characterization on account of its multiplanar capabilities, excellent soft-tissue contrast and high spatial resolution. BOTs histological subtypes display specific features on MRI that are useful in differential diagnosis. However, the final diagnosis and staging of BOTs require pathologic evaluation after surgical excision. Therefore, the purpose of this review is to describe, illustrate and compare the imaging characteristics of the different subtypes of BOTs - serous, mucinous and seromucinous - focusing on MRI, as well as to correlate with pathology findings considering the recent 2020 World Health Organization (WHO) classification, in order to improve the accuracy of preoperative diagnosis and facilitate optimal patient management.

摘要

交界性卵巢肿瘤(BOT)是一组具有组织学特征的上皮性肿瘤,其特征为无间质浸润的非典型上皮增生。这些肿瘤通常发生在生育期的年轻女性,预后良好。尽管超声检查是评估任何疑似附件肿块的主要筛选影像学技术,但灰阶和彩色多普勒在特征性诊断 BOT 方面价值有限。因此,鉴于其多平面成像能力、出色的软组织对比度和高空间分辨率,推荐盆腔磁共振成像(MRI)进行进一步特征性评估。BOT 的组织学亚型在 MRI 上显示出具有鉴别诊断意义的特定特征。然而,BOT 的最终诊断和分期需要在手术切除后进行病理评估。因此,本综述的目的是描述、说明和比较不同 BOT 组织学亚型(浆液性、黏液性和黏液浆液性)的影像学特征,重点是 MRI,并结合最近的 2020 年世界卫生组织(WHO)分类的病理学发现,以提高术前诊断的准确性,并为患者的最佳管理提供便利。

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