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17例妊娠合并卵巢交界性肿瘤的临床分析

Clinical Analysis of 17 Cases of Borderline Ovarian Tumors During Pregnancy.

作者信息

Wang Mingdan, Li Yue, Xu Tongtong, Shi Chen, Jiang Lili, Liu Kuiran

机构信息

Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.

出版信息

Front Oncol. 2022 Jul 13;12:934751. doi: 10.3389/fonc.2022.934751. eCollection 2022.

Abstract

OBJECTIVE

The study retrospectively analyzed the clinical characteristics and prognosis of 17 cases of pregnancy complicated by borderline ovarian tumors to provide help for clinical workers.

MATERIALS AND METHODS

The clinicopathological data of 17 patients with ovarian borderline tumors during pregnancy at the Shengjing Hospital of China Medical University from January 2015 to June 2021 were collected and analyzed retrospectively. The average age of the patients was 31.82 years (25-45 years), the average number of pregnancies was 2.06 times (1-6 times), and the average number of births was 0.41 times (0-1 time).

RESULTS

Among the 17 patients, 4 were diagnosed in the first trimester, 2 in the second trimester, and 11 in the third trimester. Most of the first symptoms were cysts, cyst enlargement, or cyst rupture. Among them, 3 cases (1 in the first trimester and 2 in the second trimester) continued pregnancy after a conservative operation, 9 cases underwent cesarean section and a conservative operation simultaneously, and the mother and child had a good outcome. Two cases underwent conservative operations and induced abortion, and 1 case underwent an ectopic pregnancy operation at the same time. The prognosis of the patients was good without recurrence.

CONCLUSION

Preoperative diagnosis of borderline ovarian tumors in pregnancy is delayed, and imaging and tumor markers are not specific. The coincidence rate between intraoperative frozen pathology and postoperative paraffin pathology was not high. Borderline tumors are mainly treated by surgery, and the prognosis for mothers and infants is good.

摘要

目的

回顾性分析17例妊娠合并卵巢交界性肿瘤的临床特征及预后,为临床工作者提供帮助。

材料与方法

回顾性收集并分析2015年1月至2021年6月在中国医科大学附属盛京医院就诊的17例妊娠合并卵巢交界性肿瘤患者的临床病理资料。患者平均年龄31.82岁(25 - 45岁),平均妊娠次数2.06次(1 - 6次),平均分娩次数0.41次(0 - 1次)。

结果

17例患者中,孕早期确诊4例,孕中期确诊2例,孕晚期确诊11例。首发症状多为囊肿、囊肿增大或囊肿破裂。其中,3例(孕早期1例,孕中期2例)经保守手术后继续妊娠,9例同时行剖宫产及保守手术,母婴结局良好。2例行保守手术并引产,1例同时行异位妊娠手术。患者预后良好,无复发。

结论

妊娠合并卵巢交界性肿瘤术前诊断延迟,影像学及肿瘤标志物不具有特异性。术中冰冻病理与术后石蜡病理符合率不高。交界性肿瘤主要采取手术治疗,母婴预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95ee/9326021/6d030c343c94/fonc-12-934751-g001.jpg

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